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Toxicology > Exam 1 toxicity > Flashcards

Exam 1 toxicity Flashcards

1
Q

Bitter almond odor

A

Cyanide

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2
Q

Garlic odor

A

Organophosphates, arsenic

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3
Q

Fruity odor

A

DKA, isopropyl alcohol

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4
Q

Majority of poisoning are ______ but the majority of deaths secondary to poisoning are ______

A

Unintentional, intentional

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5
Q

1 drug used for intentional overdose

A

Acetaminophen

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6
Q

Most commonly reported poison

A

Analgesics (acetaminophen)

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7
Q

Least commonly reported

A

Alcohol

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8
Q

What is least associated with death?

A

Hydrocarbons

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9
Q

Which methylxanthine is most toxic?

A

Theophylline

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10
Q

Acetaminophen antidote

A

NAC

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11
Q

Benzo antidote

A

Flumazenil

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12
Q

Carbamate insecticides antidote

A

Atropine

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13
Q

Lead antidote

A

EDTA

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14
Q

Opioids antidote

A

Naloxone

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15
Q

Organophosphate antidote

A

Atropine and pralidoxime

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16
Q

What is the dose-response curve

A

Drug response is proportional to dose

17
Q

When maximal drug response is reached it is known as the?

A

Ceiling effect

18
Q

What is the dose necessary to produce half the max response?

A

ED50; used to compare potency of drugs

19
Q

What is the smallest amount of a drug that will produce a therapeutic effect?

A

Minimal dose

20
Q

What is the initial high dose used to quickly evaluate blood levels of drug?

A

Loading dose

21
Q

What is the largest amount of a drug that will produce desired effect without producing sx of toxicity

A

Maximum dose

22
Q

What is the dose that is customarily given to produce desired effect?

A

Therapeutic dose

Toxicology (2 decks)

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