final lecture 1 Flashcards
factor 2a
thrombin
factor 2
prothrombin
factor 1a
fibrin
what factors need Ca to be activated?
9->9a, 10->10a, 2->2a, 7->9a
neutropenia
abnormally low number of neutrophils
mild neutropenia
1000<1500- minimal risk of infection
moderate neutropenia
500<1000- moderate risk of infection
severe neutropenia
ANC<500- severe risk of infection
thrombocytopenia
decrease in plts <100,000
causes of decreased plts
decreased production
increased destruction
medication induced-myelosuppression
hematopoietic growth factors are active at ____
low concentrations
networking
hematopoietic growth factors interacting synergistically with other factors
proteins produced in prokaryotes(bacteria)
show no glycosylation (Carb moiety)
proteins produced in eukaryotes(yeast, mammals)
are glycosylated
stem cell factor (SCF) is a
cytokein/hematopoietic growth factor involved in regulation of early stages of hematopoeisis