Functional genomics Flashcards Preview

BIO2030 Biotechnology > Functional genomics > Flashcards

Flashcards in Functional genomics Deck (6)
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1

What is functional genomics?

Understanding biological functions through the use of genomic/transcriptomic data
Investigation of cell functions
Assigns functions to genes

2

What are some methods in transcriptomics?

Northern blots
in situ hybridisation
RT-qPCR
digital droplet PCR
Microarray
RNA-seq

3

What are some methods in proteomics?

2DE-MS
LC/MS
Metalloproteomics
Phosphoproteomics
Structural genomics

4

What is the transcriptome?

The set of all the mRNA in a cell

5

What are the discrepancies between protein and mRNA in cells?

mRNA levels do not always correlate with protein levels in a cell

6

What are protein arrays used for?

Detection of biomarkers
Protein quantification in cell lysate
Protein: protein interactions
Antibody characterisation