Gastro in class Flashcards

1
Q

ALP elevation can indicate disease in ___, mild elevations can be seen in __

GGT elevations in ___ as well as ___

Helps to support that __ is from liver/biliary system and not ____

Very abnormal to see __ in the urine

INR/PT assess extrinisc path factors such as

best prognostic lab value for

Liver dz usually has __ albumin

A

biliary tract, parenchymal liver dz

biliary dz, drugs/alcohol

inc ALP, bone

direct bilirubin

2, 7, 9, 10

fulminant hepatic failure

low

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2
Q

Biliary colic due to ___ lodged in ___ such as ___

findings
Constant ___
__ usually present
may mimic acute ___

w progression, pain should be ___, localize to ___, sx include __ and __,, indicating

Uncomplicated biliary colic does not have ___ or ___

Liver fxn tests are

A

gallstone, biliary system, cystic duct

epigastric, RUQ
NV
acute MI

sharp, RUQ, fever/leukocytosis, acute cholecystitis

fever, peritoneal inflam

normal

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3
Q

Ab pain from ___ is ___, not

caused by ____

ab wall pain is __ and ___

somatic pain occurs following ___ such as __ progressing to ___

localized sensation caused by inflam of ___

visceral pain often seen in __, meaning exams are __

A

visceral organs, vague, sharp

bowel distension, contraction, ischemia

focal, tender

progression of process, biliary colic-acute cholecystitis

peritoneal surface

center of ab, paramount

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4
Q

Biliary colic presentation w abnormal LFTs should indicate C, C, M, E

Esophageal ca main sx __ and ___

Predisposing factors include T/A, L, B

Gerd cardinal sx ___, can lead to ___
malignant change usually occurs in ___

Nasal regurg, weakness, dysphagia seen in __ such as ___

A

cholangitis, choledocholithiasis, Mirizzis syndrome, emphysematous cholecystitis

progressive dysphagia, wl

Tobacco, alcohol, lye, barrett’s esophagus

pyrosis, Barrett’s epithelium, distal esophagus

neuro disorder, ALS

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5
Q

Gynecomastia- diff from
can be __ in adolescence

usually due to __ such as C, H, U, D

AA w/out diffuse peritonitis (no __) has only ____ via inflamed appendix touching ___

best test for this

__ and __ only seen w diffuse irritation

A
fatty tissue (lipomastia)
physio

inc estrogen, cirrhosis, hormone prod tumors, unrecognized ingestion, drugs

RT, focal inflammation, membrane

rovsings sign

psoas/obturator sign

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6
Q

Rectus sheath hematoma
spontaneous/traumatic bleeding into ___ causing __ ab pain

usually occurs in setting of __ (look for___)
should not have findings of ___
Therapy for __ and __

Psoas sign can be seen in ___ and __ and ___

many cases of AA are

Reticuloendothelial splenomegaly infections such as

Gradnulomatous dz such as

__ dz

A

muscle sheath, focal

bleeding do, anticoag
visceral ab pain
bleeding do, pain

posterior pointing appendicitis, abscess, diverticulitis

not positive

mono, parasites, fungal

sarcoid

deposition dz

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7
Q

Free intraperitoneal air must be differentiated from ____

usually indicates rupture of
findings should show

Benign free air can occur ___, extension of

Reason for upright chest in acute ab xray series

Duodenal ulcer related to
More common than

Sx relieved by

Comps inc perf w __ or ___ or ___

No __ potential

A

normal gastric/colonic gas

stomach/intestine
ab pain, diffuse peritonitis

post ab surgery. pneumomediastinum

perf duodenal ulcer w intra-peritoneal air

H pylori, NSAIDs

gastric ulcer

food

peritonitis, panc, hemorrhage

malignant

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8
Q

Wilsons dz copper deposition due to congenital lack of ___
inheritance

Involves L, E, K, B, B/J
High serum copper can produce ___

cobalt overload leads to
Fulminant hepatic failure from ___ ingestion (amanita phylloides)

predisposition to mesenteric ischemia

A

ceruloplasmin
AR

liver, eye, kidney, basal ganglia, bone/joint
hemolytic anemia

heart failure
toxic mushroom

heart disease, Afib

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9
Q

Hemochromatosis inheritance
Fe overload leads to __ and ___, ___, ___
arthritis usually seen in

high risk for ___
alcohol use exacerbates ___

buzzword

Acute blood loss leads to minimal change in

Hemodilution only occurs w

Judge blood loss via __

A

AR
cirrhosis, skin discolored, endocrine dz, heart dz
2/3 digits at MCP

secondary hepatoma
liver dz

bronze diabetes

hct

fluid shift from extravascular space

vitals (HR/BP)

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10
Q

Conjugated bilirubin usually not seen in ___, but when present, is filtered by kidney, showing ___

Urine w high bilirubin rxn and no urobilinogen indicates inc ___ w bilrubin blocked from ___

dx is

Cirrhosis has ___ urine billirubin and ___ urobilinogen

Hemolysis has __ urine urobilinogen and __ blood rxn of hb from inc __, but ___ bilirubin rxn

A

blood, dark urine (+ rxn)

serum conj bilirubin, gut

choledocholithiasis

+. +

+. +. -

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11
Q

Pt w jaundice, pruritis, cholestatic labs has process involving ___. such as __ and __

or small ducts such as ___ or ___ or ___

use __ to differentiate

Carotenemia can produce

normal sized spleen should be found ___

hepatomegaly usually indicated by > ___ on MCL

A

large biliary ducts, cholangiocarcinoma, panc cancer

PBC, infiltrative dz, drugs

imaging

yellowing of skin

posterior to mid axillary line

12cm

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12
Q

Enlarged liver can be due to H, P, C, C, H

Epigastric pain could be

duodenal ulcer/ruptured spleen can radiate to

biliar colic can radiate to

acute panc/renal colic can radiate to

uterine/rectal pain can radaite to

A

hep, passive congestion, cancer, cirrhosis, hep vein thrombosis (Budd Chiaria syndrome)

peptic ulcer, GB dz, panc, MI

right shoulder

r scapula

midback

sacrum

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13
Q

Hep LFT is __ and hyperbilirubinemia is __

Chronic active HepB pt usually has __ progressing to__ and at risk for __

Hep C risk factos I, S
Dx test is

Malaria leads to

potential causes of chemical hepatitis W, A, M, S, C

Number 1 cause of cirrhosis leading to liver transplant

Number 1 cause of cirrhosis

A

inc, mixed

mild, const complains, cirrhosis, hepatoma

IV drugs, sex w infected person
IgM antibody to HepC

indirect hyperbilirubinemia

wilsons dz, A1AT, Mono, syphillis, CMV infection

HepC

alcohol

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14
Q

Narcotics should not produce

Shock liver can have ___ LFTs
should have hx of ___ or ___

Very high LFTs should check for ____
levels normal early, ___ later

fulminant liver failure, progressively rising __ indicate poor prog

also ___ showing liver regen

A

fulminant liver dz

extreme inc
hypoTN, heart dz

acetominophen, inc drastically

PT/INR

high serum AFP

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15
Q

Wilson dz most common in
best test is low __

best screening test for Hemochromatosis ___. should be ___

test for chronic, active, AI hep ___

if A1AT def suspected, look for ___ and order ___, should be __

Screen for hepatoma w ___ should be __, important cause of ___ in cirrhosis pt

A

YM, ceruloplasmin

serum iron/TIBC
high

ANA, ASMA

lung dz, A1AT enzyme levels
low

AFP, high
decompensation

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16
Q

Massive tropical splenomegaly T, M, C, V, C, L
Schistosomiasis from M, M, J

S haematobium involves __
pt presents w __ and ___
feared complication is

GERD rf H, O, O, A/A, S

Pathogenesis
Pyrosis caused by __ contacting inflamed mucosa (esophagitis)
other sx

Dysphagia + GERD suggests

comps

A

thalassemia, myelofibrosis, chronic malaria, visceral leishmaniasis, CML, lymphoma
Mansoni, mekongi, japonicum

urinary tract
terminal hematuria, dysuria
bladder ca (SCC)

Hiatal hernia, obesity, older, alcohol/tob, scleroderma

reflux
cough, hoarse, chest pain, aspiration

peptic stricture

cancer in distal esoph (adenocarc) and esoph stric

17
Q

AA pathogenesis
Sequence of findings
EP, ANV, D, F, L

Diverticulitis seen in __ colon usually

impacted fecalith leads to __ and __ or __

Age 
Pain located
No 
Bowel habit
Fever/leuko is 
Later pain/tenderness in
A

obstructing fecalith
epigastric pain, ANV, deep tenderness, fever, leukocytosis

left

ischemia, abscess, rupture

older
hypogastric
NV
diarrhea
pronounced
LLQ/suprapubic
18
Q

PUD commonest sx, described as
location

comps

Gastric/Duodenal
Age
Effect of food
Cancer potential

A

pain/discomfort (gnawing/burning/sharp)
Epigastric, LUQ

bleeding, perf, panc, GOO

G- 6th decade, less reliable, yes
D- younger, relief, no

19
Q

Acute panc assc w

Pain located __ and assc w

Acute Pyelonephritis
cause- ___ of UBUK, __ or ___

PF D, M, U, R

Sx
Urethral
bladder
kidney

Pain is ___ and __ due to stretching of __
may radiate to __
other sx D, F, U, C, O

Exam findings

A

alcohol abuse, gallstone

epigastric/back, NV

ascending infection, urethra/bladder/ureter/kidney

diabetes, multiple sex partners, URI, renal stone

dysuria
suprapubic pain
cva pain

dull, steady, renal capsule
umbilicus
Dysuria, freq, urgent, cloudy, odor

CVA tenderness, suprapubic tenderness