Germ Cell Tumors Flashcards Preview

COMLEX 2 > Germ Cell Tumors > Flashcards

Flashcards in Germ Cell Tumors Deck (15)
Loading flashcards...
1
Q

yolk sac tumor histo

A

multiple histo patterns
may be microcytic, papillary, reticular, glandular, solid or hepatoid
schiller-duval bodies present in 50%

2
Q

yolk sac tumor AFP

A

elevated (>100)

3
Q

yolk sac tumor ß-hCG

A

negative

4
Q

choriocarcinoma histo

A

abundant necrosis and hemorrhage, mixed cytotrophoblasts and syncitiotrophoblasts

5
Q

choriocarcinoma AFP

A

negative

6
Q

choriocarcinoma ß-hCG

A

elevated (often >1000)

7
Q

teratoma histo

A

mature and immature components

mature: skin with adnexa, respiratory tract epithelium, GI epithelium, glial tissue
immature: undifferentiated, often primitive neuroepithelium

8
Q

teratoma AFP

A

negative

9
Q

teratoma ß-hCG

A

negative

10
Q

seminoma histo

A

classic seminoma: clonal cells with well-defined cytoplasmic borders; central nuclei with prominent nucleoli; and clear, glycogenated cytoplasm

11
Q

seminoma AFP

A

negative

12
Q

seminoma ß-hCG

A

may be mildly elevated

13
Q

embryonal histo

A

rarely present in pure form; demonstrates clusters and sheets of markedly atypical cells
may contain syncitiotrophoblast cells

14
Q

embryonal AFP

A

may have mild elevation, <60

15
Q

embryonal ß-hCG

A

may be mildly elevated