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Flashcards in GI Development - Sev Deck (11)
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1
Q

The lining of the digestive system and its related glands develop from endoderm. EXCEPT the precursors to the anus, mouth and anterior pituitary (Stomodeum + proctodeum). They are lined by ____________.

A

Ectoderm

2
Q

Pathology resulting from failure of esophagus to lengthen sufficiently?

A

Congenital hiatal hernia

Stomach is drawn up into the thorax

3
Q

Blood supply of foregut, midgut, and hindgut?

A

Foregut: Celiac artery (except pharynx/esophagus)
Midgut: superior mesenteric
Hindgut: inferior mesenteric

4
Q

Where in the adult gut is the transition between midgut and hindgut derived structures?

A

Division is the middle of the transverse colon.

5
Q

Hematopoietic cell development occurs in this organ during fetal life?

A

spleen

sometimes reverts in adults too

6
Q

Pancreas develops from endoderm. Ventral and dorsal pancreas fuse together. Which duct will usually become the definitive pancreatic duct after the two tissues merge?

A

The duct of the ventral pancreas becomes the definitive duct

7
Q

What can be formed by the omphaloenteric duct (or yolk stalk) in the adult?

A

In an adult its called an ileal (meckel) diverticulum

8
Q

What structure serves as the axis for counter-clockwise rotation of the the midgut 270 degrees?

A

Superior Mesenteric artery

9
Q

Explain the basic difference between a congenital omphacele, umbilical hernia, and gastroschisis:

A

Omphacele: Intestinal loops fail to re-enter abdominal cavity in development. Loop is covered by amnion

Unbilical Hernia: Abdominal muscles fail to close umbilical ring. Protrusion covered by subcutaneous tissue and skin

Gastroschisis: Defect in abdominal wall. Contents protrude and there is no overlying sac involved.

10
Q

Pathology behind Hirschsprungs Disease?

A

Failure of the neural crest cells to migrate appropriately. Parasympathetics in the wall of the colon are then missing

11
Q

What is the embryological problem behind an imperforate anus?

A

Urogenital septum division issue