*Glomerulonephritis Flashcards Preview

The Renal System > *Glomerulonephritis > Flashcards

Flashcards in *Glomerulonephritis Deck (11)
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1
Q

What comprises the renal parenchyma?

A

Tubules

Interstitium

Glomeruli

2
Q

What is the most common cause of end stage renal failure?

A

Diabetes

(2nd is glomerulonephritis)

3
Q

What is glomerulonephritis?

A

Immune-mediated disease of the kidney affecting glomeruli

4
Q

What can initiate the immune response within the glomeruli within glomerulonephritis?

A

Planted antigen

Self antigen (true autoimmunity)

Antibody-antigen complexes becoming trapped

5
Q

What are the different types of lesions in glomerulonephritis?

A

Proliferative

Non-proliferative

6
Q

What is a proliferative lesion in glomerulonephritis?

A

Damage to mesangial or endothelial cells

7
Q

What is the difference between endothelial and mesangial damage in terms of presentation?

A

Creatinine is normal in mesangial damage and rasied in endothelial

8
Q

In which type of lesion in GN involves red cell casts in the urine?

A

Proliferative

9
Q

What is a non-proliferative lesion in GN?

A

Damage to podocytes

10
Q

Which type of lesion causing GN involves proteinuria?

A

Non-proliferative

11
Q
A