Hematology

Question 0

FFP (fresh frozen plasma)

Answer 0

Contains all of the clotting factors
No RBCs/WBC/platelets
Given for hi PT/PTT, coagulopathy, def of clotting factors
Vit K takes too long
F/u PT and PTT

Question 1

PRBC

Answer 1

Mix with NS but not LR (coagulation)
Each unit inc Hct by 3-4 pts
90 to 120 min
Check CBC after infusion

Question 2

Cryoprecipitate

Answer 2

Factor VIII and fibrinogen

Hemophilia A, DIC, vWD

Question 3

Platelet transfusion

Answer 3

1 unit incr platelet count by 10,000

Question 4

What are indications for whole blood transfusions?

Answer 4

Massive blood loss

Blood should be warmed to prevent a decrease in core body temp

Question 5

Target cells

Answer 5

B thalassemia major,

HbF and Hb A2 are elevated

Question 6

Acquired causes of sideroblastic anemia

Answer 6

Rx: chloramphenicol, INH, EtOH

Lead exp, collagen vascular dx, neoplastic dx (myelodysplastic)

Question 7

Rx for sideroblastic anemia

Answer 7

Pyridoxine

Remove offending agents