Hepatitis/Liver Disease Flashcards Preview

NAPLEX Flashcards > Hepatitis/Liver Disease > Flashcards

Flashcards in Hepatitis/Liver Disease Deck (19)
Loading flashcards...
1

Sovaldi

Sofosbuvir

2

Harvoni

Sofosbuvir + ledipasvir

3

Epclusa

Sofosbuvir + Velpatasvir

4

Vosevi

Sofosbuvir + Velpatasvir + Voxilaprevir

5

Mavyret

Glecaprevir + Pibrentasvir

6

Viekira Pak

Paritaprevir/ritonavir/Ombitasvir + Dasabuvir

7

Suffix for NS3/4A PIs

-previr

8

Suffix for NS5A replication complex inhibitors

-asvir

9

Suffix for NS5B polymerase inhibitors

-buvir

10

Zepatier

Elbasvir/grazoprevir

11

HCV treatment algorithm

2-3 DAAs +/- ribavirin x 12 weeks
Mavyret x 8 weeks

12

Pan-genotypic DAAs

Epclusa, Mavyret

13

DAAs that have DDI with acid suppressant therapy

Harvoni, Epclusa, Vosevi

14

DAAs that treat HCV/HIV co-infection

Harvoni, Epclusa, Mavyret

15

DAAs salvage therapy

Vosevi, Mavyret

16

Ribavirin SE

Teratogenic, hemolytic anemia

17

Drugs used to treat HepB

(NRTIs) TDF, TAF, lamivudine, telbivudine, entecavir, adefovir

18

Hepatotoxic drugs (d/c if LFTs > 3x ULN)

APAP, isoniazid, nevirapine, NRTIs, tipranavir, valproic acid

19

Drugs for relapse prevention for alcoholic liver disease

Naltrexone (ReVia, Vivitrol)
Acomprasate (Campral)
Disulfiram (Antabuse)