Histology: principles, respiratory, cardio, GI. Flashcards

1
Q

What lines the nasal cavity?

A

Keratinised stratified squamous epithelium

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2
Q

What lines the majority of the respiratory system?

A

Pseudostratified ciliated columnar epithelium with goblet cells, aka respiratory epithelium.

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3
Q

What lines the oropharynx?

A

Non-keratinized stratified squamous epithelium.

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4
Q

What is the larynx made up od?

A

Cartilage and muscles lines by respiratory epithelium

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5
Q

What is the trachea lined by?

A

Respiratory epithelium backed by a basal lamina, a lamina propria.

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6
Q

What are the bronchi lined by?

A

respiratory epithelium, and a lamina propria containing a discontinuous layer of smooth muscle and seromucous glands.

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7
Q

Describe the epithelium changes as you progress down the respiratory tree to the smallest bronchioles.

A

Epithelial cells decrease in height from columnar to cuboidal.

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8
Q

What lines the terminal bronchioles?

A

Cuboidal epithelium, with ciliated and non-ciliated club cells.

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9
Q

What lines respiratory bronchioles?

A

Discontinuous squamous type I alveolar cells.

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10
Q

What lines alveoli?

A

Type I and II alveolar cells (pneumocytes). Alveolar macrophages are also present.

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11
Q

Describe type I alveolar cells.

A

Simple squamous epithelium lining alveolar surface and permeable to gases.

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12
Q

Describe type II alveolar cells.

A

Polygonal, dense membrane bound lamellar bodies containing surfactant.

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13
Q

What are less common microbiological causes of community acquired pneumonia?

A

Mycoplasma pneumonia, coxiella burnetti, chlamydia.

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14
Q

How to confirm atypical pneumonia in lab?

A

serology of bloods (gold top vacutainer), PCR on swabs/secretions.

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15
Q

Mycoplasma pneumonia.

A

common cause of atypical community acquired pneumonia, highest incidence in children and young adults. Spread by person to person.

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16
Q

Coxiella burnetti.

A

Cause of pneumonia and Q fever. Uncommon, spread from sheep and goats to humans. Complications include culture negative endocarditis.

17
Q

Chlamydophilia psittaci.

A

Causes psittacosis, uncommonly caught from pet birds. Usually presents as pneumonia.

18
Q

What defences exist in the nasopharynx?

A

Nasal hairs, ciliated epithelia, IgA.

19
Q

What bacteria typically colonises the URT?

A

Gram+ve: alpha-haemolytic strep. e.g. strep. pneumoniae, beta-haemolytic strep. e.g. strep pyrogenes, and staphylococcus aureus.
Gram -ve: haemophilus influenza, Moraxella catharalis.

20
Q

Define pleura, and what is its hallmark of disease.

A

The pleura is a mesothelial surface lining the lungs and mediastinum. Mesothelial cells are designed for fluid absorption, and therefore the hallmark of pleural disease is pleurla effusion.