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Flashcards in immunology Deck (10)
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1

what does SPUR stand for ?

S - serious infections = unresponsive to oral antibiotics
P - persistent infections = early structural damage, chronic infections
U - unusual infections = unusual organisms and sites
R - recurrent infections = two major or one major and one minor recurrent minor infections in one years

2

what is a secondary immunodeficiency disorder?

common, often subtle, often includes more than one component of immune system

3

what conditions are associated with secondary immune deficiency?

- ageing, measles, anti-cancer agents, leukaemia, malnutritions

4

what is a primary immunodeficiency disorder (PIDs) - resp ?

- resp are main ones
- pulmonary complications cause significant morbidity and mortality in patients with PIDs
- early diagnosis and appropriate treatment can prevent or at least slow the development of resp complications

5

what are the upper resp complications of PIDs?

- sinusitis
- otitis media
- laryngeal angioedema

6

what are the lower resp complications of PIDs?

- malignancies
- interstitial lung diseases
- pneumonia
- bronchitis, bronchiectasis

7

what is the most frequent associated PID of sinusitis and otitis media?

- primary antibody deficience (PAD)

- selective IgA deficiency

8

what should be considered in patients with laryngeal angioedema?

- complement system disorders

9

what is the most frequent manifestations of many PIDs?

pneumonia

10

what happens as your neutrophils count increases?

your risk of disease decreases