Flashcards in Immunotherapy Deck (6):
What is immunotherapy?
Artificial stimulation of the immune system to fight cancer. Target immune checkpoints (e.g. PD1)
Why does it cause SEs?
Blocks immune checkpoint control. think like 'taking the brakes off someone's immune system'
SEs therefore mimic autoimmune/ inflammatory disease
Give examples of SEs for:
Skin, GI, renal, endocrine, liver, eyes, resp, neuro, msk
Skin: rash (can mimic any kind)
Endo: thyroid, pituitary (can be fatal)
Eye: acute uveitis
What test is important re: pituitary SEs
What is the peak time for occurrence of immuno SEs
6-8 weeks post-treatment (but can occur <6 months after)