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Flashcards in Independent Prescribing Deck (125)
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1
Q

Define competency

A

A quality or characteristic of a person that is related to effective performance, competencies can be described as a combination of knowledge

2
Q

When did the RPS release the new competency framework for all prescribers?

A

JULY 2016

3
Q

List the competencies 1-6 required in the ‘consultation’ section of the prescribing framework

A

1) assess patient
2) consider the options
3) reach a shared decision
4) prescribe
5) provide information
6) monitor and review

4
Q

List the competencies 7-10 in the ‘prescribing governance’ part of the prescribing framework

A

7) prescribe safely
8) prescribe professionally
9) improve prescribing practice
10) prescribe as part of a team

5
Q

Two types of independent prescriber:

A

1) prescribe licensed meds within clinical competence

2) a community practitioner nurse can prescribe against formulary in BNF

6
Q

What’s supplementary prescribing?

A

Voluntary partnership between doctor/dentist and a supp prescriber to prescribe against an agreed patient-specific clinical management plan

7
Q

What proportion of MURs should community pharmacists provide to 4 target groups?

A

70%

8
Q

What are the four target groups for an MUR

A

1) high risk meds (NSAID, anticoagulants, anti platelets &diuretics)
2) patients recently discharged from hosp who have had changes
3) patients with respiratory disease
4) patients at risk of or diagnosed with CVD & being prescribed more than 4 meds

9
Q

What’s NMS

A

New medicines service- was the 4th advanced service to be added to the community pharmacy contractual framework

10
Q

Name 4 conditions/therapy areas that were selected to be included in the initial NMS rollout:

A

1) asthma and COPD
2) type 2 diabetes
3) antiplatelet/ anticoagulant therapy
4) hypertension

11
Q

What are the 5 headings that are included in the Cambridge-Calgary observation guide

A

1) initiating the session
2) gathering information
3) physical information
4) explanation and planning
5) closing the session

12
Q

What heading in the Cambridge-Calgary observation guide can be left out?

A

Physical examination

13
Q

When did the NHS put £15million in to a 3 year scheme for pharmacists in GP practices

A

JULY 2015

14
Q

The GP forward view published in April 2016 suggests by 2020 what?

A

1500 pharmacists could be working in GP practices and extra funding in the region of £112 million will be made available for this

15
Q

What 4 key areas can pharmacists help with in GP surgeries?

A

1) clinical services
2) prescription management
3) audit and education
4) medicines management

16
Q

Do supplementary prescribers need to complete the independent prescribing course?

A

NOPE

17
Q

What three CDs can pharmacist independent prescribers NOT prescribe?

A

Diamorphine, dipipanone or cocaine for treatment of addiction

18
Q

List the 12 objective signs of opiate withdrawal

A
Yawning 
Coughing 
Sneezing 
Runny nose
Lachrymation 
Raised BP
Increased pulse
Dilated pupils
Cool, clammy skin 
Diarrhoea
Nausea 
Fine muscle tremor
19
Q

List 7 subjective signs of opiate withdrawal

A
Restlessness 
Irritability
Anxiety 
Sleep disorders 
Depression 
Drug craving 
Abdominal cramps
20
Q

What does DSM V stand for

A

Diagnostics and statistics manual

21
Q

What does ICD-10 stand for?

A

International classification of diseases

22
Q

What can be a consequence of chronic intravenous injecting

A

Poor vascular return

23
Q

Psychosis can be precipitated by what?

A

Amphetamine use

24
Q

In substance misuse what 3 factors does zinbergs model include

A

Drug
Set
Setting

25
Q

Name the two licensed treatments available in the U.K. To treat opiate dependence via substitution therapy

A

Methadone

Buprenorphine

26
Q

Why should an ECG be done before increasing the methadone dose to over 100mg

A

Because there’s a link with prolonged QRc and torsades des pointes syndrome

27
Q

What drug is licensed and used in opiate withdrawal under ‘supportive pharmacological therapy’

A

The alpha-adrenergic blocker lofexidine

28
Q

Is cocaine dependence supported by pharmacological interventions?

A

NO

29
Q

What are the 5 main sections in the guidance on capacity/confidentiality/consent?

A
Seeking consent
Adults without capacity 
Children & young peeps
Withdrawing & withholding life-sustaining treatment 
Other exceptions to the principles
30
Q

Name two types of informed consent

A

Implicit

Explicit

31
Q

When a patient is ‘informed’ what does this mean

A

1) they have sufficient info in a format and language they understand
2) they can remember info for long enough to make decision
3) they can weigh up pros/cons
4) they can make a decision about whether the treatment is appropriate for their needs

32
Q

When did the DH publish ‘confidentiality :NHS code of practice’

A

July 2003

33
Q

The data protection act 1998 is built around how many key principles?

A

8

34
Q

What year did the caldicott report recommend 6 key principles which govern the release and use of patient information?

A

1997

35
Q

What are the 6 caldicott principles that govern the release and use of patient information?

A

1) Justify the purpose
2) do not use patient identifiable info unless absolutely necessary
3) use the minimum necessary
4) access to patient info on need to know basis
5) everyone should be aware of their responsibilities
6) understand &comply with the law

36
Q

Each organisation should have a caldicott guardian - what are they responsible for?

A

The control of patient confidentiality throughout the organisation including assessing the relevance of clinical trials

37
Q

Name three acts related to capacity and confidentiality

A

1) data protection act 1998
2) the freedom of information act 2000
3) health and social care act 2012

38
Q

Name two acts that give patients access to medical and health records

A

1) access to medical records 1988

2) access to health records 1990

39
Q

What does ‘access to medical records 1988’ allow

A

This sets out criteria for when a patient has a right to see what is written about them in medical records

40
Q

What does ‘access to health records 1990’ allow

A

This enables a person to access medical records of a deceased individual if there is a claim arising from that death

41
Q

In difficult situations involving decisions about patients, a secondary agency may be involved this includes what 3?

A

1) a professional regulatory body
2) a local clinical ethical team
3) a court of law

42
Q

Name the two principle philosophical viewpoints in ethical decision making

A

1) utilitarianism

2) deontological

43
Q

What is utilitarianism?

A

Decision is made on the risk to benefit outcomes of all the relevant factors to the particular patient

44
Q

What is deontological?

A

Duty of care is owed to the patient

45
Q

Name the 4 theoretical ethical principles of pharmacy

A

Beneficence
Integrity
Competence
Accountability

46
Q

What are the 4 steps to ethical decision-making in pharmacy

A

1) gathering information
2) prioritisation and value judgment
3) relevant options
4) decision time

47
Q

Can supplementary prescribers prescribe for family/Friends

A

This is decided by the independent prescriber

48
Q

Can non medical independent prescribers prescribe for family/friends?

A

NO only in exceptional circumstances

49
Q

NICE guidance says someone has hypertension what they have a persistent BP above what?

A

140/90mmHg

50
Q

Patients should be treated immediately when their BP in clinic is greater than or equal to what?

A

180/110mmHg

51
Q

What is the BP target for people under 80yrs old?

A

Below 140/90mmHg or below 135/85mmHg if using ABPM/HBPM

52
Q

What’s the target BP for people aged 80yrs and over?

A

Below 150/90mmHg or below 145/80mmHg if using ABPM/HBPM

53
Q

Do patients with renal disease or diabetes have higher or lower BP targets?

A

Lower duh

54
Q

Hypertension is a major risk factor for what 6 things?

A
Ischaemic/haemorrhagic stroke
MI
Heart failure 
CKD 
Cognitive decline 
Premature death
55
Q

What is ‘essential hypertension’?

A

When the underlying cause is NOT identified

56
Q

What is ‘secondary hypertension’?

A

When the underlying cause IS identified

57
Q

Name 2 causes of secondary hypertension

A

1) renal or endocrine disease

2) drug induced

58
Q

Name 4 drugs that can induce hypertension

A

1) venlafaxine
2) COC
3) sympathomimetics
4) alcohol

59
Q

True or false: ‘patients with essential hypertension usually have normal cardiac output, but raised peripheral resistance’

A

TRUE DAT

60
Q

Vascular endothelial dysfunction has been implicated in what type of hypertension?

A

Essential hypertension

61
Q

Give a possible future therapeutic option for hypertension?

A

Modification of endothelial function through restoration of impaired nitric oxide production

62
Q

Name two non-dihydrophridine CCBs that are rarely used

A

Diltiazem

Verapamil

63
Q

Name 3 long acting dihydropyridine CCB

A

Amlodipine
Felodipine
Modified release nifedipine

64
Q

Name a short acting dihydropyridine that should be avoided due to its rapid onset of action

A

Capsular nifedipine

65
Q

Name 5 side effects of calcium channel blockers

A
Oedema (usually ankle swelling)
Headache 
GI disturbance 
Flushing 
Constipation with verapamil
66
Q

Why aren’t ACEi it’s line for over 55s and Afro Caribbeans?

A

They have lower levels of renin so lower response to these drugs

67
Q

Name 3 side effects of ACEi

A

Worsen renal function
Hyperkalaemia
Persistent dry cough

68
Q

What can cause the dry cough side effect of ACEi?

A

Build up of bradykinin

69
Q

Name 6 side effects of thiazides

A

1) Impaired glucose tolerance
2) Hypokalaemia
3) Hyponatraemia
4) Unfavourable increases in plasma lipids
5) Gout
6) Impotence

70
Q

What’s the most commonly prescribed beta blocker and why?

A

Atenolol as it is once daily and inexpensive

71
Q

Name an early short acting alpha blocker

A

Prazosin

72
Q

Which alpha blocker causes significant problems with postural hypotension, dizziness and vertigo?

A

Prazosin

73
Q

Name two longer acting alpha blockers

A

Doxazosin

Terazosin

74
Q

What can alpha blockers also be prescribed to treat?

A

Benign prostatic hyperplasia

75
Q

What type of drug is spironolactone and what do you have to be cautious of?

A

Aldosterone antagonist and be cautious of hyperkalaemia

76
Q

Why is hydralazine used as add on therapy and not alone?

A

Because it causes tachycardia and fluid retention

77
Q

What type of drug is hydralazine

A

Short acting non-selective vasodilator

78
Q

What drug is marketed as a topical solution for male pattern baldness because of its hair growth side effects?

A

Minoxidil

79
Q

Name two vasodilators used as add on therapy in more severe hypertension

A

Hydralazine

Minoxidil

80
Q

Name 3 centrally acting antihypertensive drugs

A

Clonidine
Methyldopa
Moxonidine

81
Q

Name three centrally acting antihypertensive drugs

A

Clonidine
Methyldopa
Moxonidine

82
Q

Name the only direct renin inhibitor

A

Aliskiren

83
Q

In 2009 the MHRA issued warning about what risks with aliskiren?

A

Warnings relating to angioedema and renal dysfunction

84
Q

What is the BP target of people with type two diabetes?

A

<140/80

85
Q

What is the BP target for people with type 2 diabetes at ‘high risk’

A

<130/80

86
Q

What’s first line choice for diabetics with hypertension?

A

ACEi

87
Q

Why should the elderly with hypertension be treated less aggressively?

A

FALLS RISK

88
Q

Should thiazides be avoided in patient with eGFR <30ml/min

A

Yes because they are ineffective

89
Q

Treatment of people with renal failure and hypertension may involve what?

A

Salt restriction and loop diuretics

90
Q

Use of ACEi for hypertension in pregnancy is associated with what?

A

Oligohydramnios
Renal failure
Intrauterine death

91
Q

What’s the first line antihypertensive in pregnancy?

A

Labetolol

92
Q

What can be given in secondary care when there is a hypertensive crisis?

A
IV:
Labetalol
GTN
Phentolamine
Esmolol
Hydralazine
Sodium nitroprusside
93
Q

What is coronary heart disease?

A

When flow of oxygen rich blood to heart is blocked or reduced

94
Q

Increased strain on the heart in coronary heart disease can lead to what?

A

Angina
Heart attack
Heart failure

95
Q

What does TIA stand for and what is it?

A

Transient ischaemic attack- like a stroke but blood flow to brain is only temporarily blocked

96
Q

What is peripheral arterial disease?

A

Occurs when there’s a blockage in arteries to limbs- usually legs

97
Q

Name 4 classes of cardiovascular disease

A

Coronary heart disease
Stroke & TIAs
Peripheral arterial disease
Aortic disease

98
Q

The NHS check over 40s CVD risk how often?

A

Every 5 years

99
Q

What does the QRisk-2 calculator work out?

A

Works out the risk of having a heart attack or stroke over the next 10years

100
Q

When can you not use the QRisk-2 score?

A

1) people who already have a diagnosis of heart disease or stroke
2) people with type 1 diabetes
3) people with eGFR< 60ml/min/1.73m^2
4) over 84years old

101
Q

What drug and strength is given to lower cholesterol for primary prevention to those with 10% greater 10 year risk of stroke/MI

A

Atorvastatin 20mg

102
Q

Name 3 drug treatments for smoking cessation

A

NRT
bupropion
Varenicline

103
Q

What’s the clinical adverse effect of bupropion

A

Increased risk of seizures

104
Q

Which treatment used in smoking cessation has an affected efficacy if it’s been previously used

A

Bupropion

105
Q

What drug interactions occur with bupropion

A

Those known to lower seizure threshold (antipsychotic, some antidepressants, tramadol, quinolone) and monoamine oxidase inhibitors

106
Q

What are the clinical adverse effects of varenicline

A

MI

Depression

107
Q

What are the three A’s to help patients stop smoking

A

ASK
ADVISE
ACT

108
Q

Name 5 categories of complementary therapies classified by the US national institute of health (NIH)

A

1) healing systems
2) mind-body connections
3) dietary supplements
4) manipulation & touch
5) restoring natural energy forces

109
Q

What is valerian used for?

A

GSL mild sedative and hypnotic

110
Q

For CAM, the MHRA assesses the quality and safety of herbal medicines bearing what?

A
Product licence (PL)
Traditional herbal registration (THR) number
111
Q

Name 3 types of insomnia

A

1) transient insomnia
2) short term insomnia
3) chronic insomnia

112
Q

What BMI is classed as overweight?

A

25-29.9 kg/m^2

113
Q

What BMI is classed as obese?

A

Over 30kg/m^2

114
Q

Patients using statins for primary prevention of CVD should aim for what percentage reduction in non-HDL levels?

A

Greater than 40%

115
Q

Name 6 classes of drug that can cause drugs

A
Corticosteroids 
Benzodiazepines 
Levodopa
Anticonvulsants 
Isotretinoin
CCB
116
Q

Name two classes of drug that can cause insomnia

A

Diuretics

CNS stimulants

117
Q

Short term insomnia is less than what?

A

4 weeks

118
Q

Long term insomnia is more than what?

A

4 weeks

119
Q

Name 6 interventions used for long term insomnia

A

1) stimulus-control therapy
2) sleep restriction therapy
3) relaxation training
4) paradoxical intention
5) biofeedback
6) CBT

120
Q

Name three drugs used to treat acute insomnia

A

Zopiclone
Temazepam
Loprazolam

121
Q

NICE CG127 is what guidance?

A

Hypertension in adults: diagnosis and management

122
Q

What is the NICE guidance CG90 for?

A

Depression in adults

123
Q

What are the ICD-10 two key symptoms of depression

A

Low mood, loss of interest and pleasure and loss of energy

124
Q

For people starting antidepressants who are at low risk when should you see them?

A

After 2 weeks then at intervals of 2-4 weeks for the first 3 months

125
Q

For people starting antidepressants who are at high risk when should you see them?

A

After 1 week