composition of nucleus pulposus
fibrocartilage
what is the water concentration in the lumbar nucleus pulposus at birth and after 30
birth = 88% 30 = 70%
consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus
nucleus pulposus will loose water under deformation conditions
cell associated with the nucleus pulpous until age 11
notochord cells
cell associated with the mature nucleus pulposus
reticulocyte-fibroblast and chondroblast
organizational pattern for collagen fibers in the nucleus pulposus
they are irregularly orientated and randomly scattered
general tissue location is described as having an abundance of collagen type II fibers
cartilage
role of collagen type II fibers based on locations where it is dominant
it appears to be related to tissues having a deformation - reformation ability
type of collagen that is dominant in the nucleus pulposus
collagen type II
appearance of the cervical annulus fibrosus
horse-shoe with anterior margin thick and the lateral margins tapering to the uncinate processes; the posterior margin is thin
compensates for thinness of the posterior part of the cervical annulus fibrosus
posterior longitudinal ligament
organization of the lumbar annulus fibrosus
12-14 concentric cylindrical lamellae
why is the posterior part of the lumbar annulus fibrosis more susceptible to rupture, herniation, prolapse, or protrusion
posterior margin of each lamellas is thing and the posterior longitudinal ligament is also less developed
what is the water concentration in the lumbar annulus fibrosis at birth and after
30 yo
birth = 78% \+30= 70%
organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus
typically have a binding site for hyaluronic acid and are thus aggregated
type of collagen that is dominant in the annulus fibrosus
collagen type I
organization of collagen fibers in the annulus fibrosus
they are parallel with one another in a single lamellas and angled
organization of collagen fibers between lamellae
collagen fibers will be angled in the opposite direction such that a spiral- counter spiral organization is observed
average angle of collagen fibers within the annulus fibrosus
average 50-60*
the attachment site for collagen fibers within the annulus fibrosus
collagen fibers of the OUTER lamellae will become SHARPEYs fibers and penetrate EPIPHYSEAL RIMS
collagen fibers of the INNER lamellae will attach to the CARTILAGINOUS ENDPLATE
origin for cells of the annulus fibrosus
sclerotomites
cell type associated with the annulus fibrosus
fibroblast and fibrocyte