Intervertebral Disc: Nucleus Pulposus/ Annulus Fibrosus Flashcards Preview

Spinal Final > Intervertebral Disc: Nucleus Pulposus/ Annulus Fibrosus > Flashcards

Flashcards in Intervertebral Disc: Nucleus Pulposus/ Annulus Fibrosus Deck (22)
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1
Q

composition of nucleus pulposus

A

fibrocartilage

2
Q

what is the water concentration in the lumbar nucleus pulposus at birth and after 30

A
birth = 88%
30 = 70%
3
Q

consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus

A

nucleus pulposus will loose water under deformation conditions

4
Q

cell associated with the nucleus pulpous until age 11

A

notochord cells

5
Q

cell associated with the mature nucleus pulposus

A

reticulocyte-fibroblast and chondroblast

6
Q

organizational pattern for collagen fibers in the nucleus pulposus

A

they are irregularly orientated and randomly scattered

7
Q

general tissue location is described as having an abundance of collagen type II fibers

A

cartilage

8
Q

role of collagen type II fibers based on locations where it is dominant

A

it appears to be related to tissues having a deformation - reformation ability

9
Q

type of collagen that is dominant in the nucleus pulposus

A

collagen type II

10
Q

appearance of the cervical annulus fibrosus

A

horse-shoe with anterior margin thick and the lateral margins tapering to the uncinate processes; the posterior margin is thin

11
Q

compensates for thinness of the posterior part of the cervical annulus fibrosus

A

posterior longitudinal ligament

12
Q

organization of the lumbar annulus fibrosus

A

12-14 concentric cylindrical lamellae

13
Q

why is the posterior part of the lumbar annulus fibrosis more susceptible to rupture, herniation, prolapse, or protrusion

A

posterior margin of each lamellas is thing and the posterior longitudinal ligament is also less developed

14
Q

what is the water concentration in the lumbar annulus fibrosis at birth and after
30 yo

A
birth = 78%
\+30= 70%
15
Q

organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus

A

typically have a binding site for hyaluronic acid and are thus aggregated

16
Q

type of collagen that is dominant in the annulus fibrosus

A

collagen type I

17
Q

organization of collagen fibers in the annulus fibrosus

A

they are parallel with one another in a single lamellas and angled

18
Q

organization of collagen fibers between lamellae

A

collagen fibers will be angled in the opposite direction such that a spiral- counter spiral organization is observed

19
Q

average angle of collagen fibers within the annulus fibrosus

A

average 50-60*

20
Q

the attachment site for collagen fibers within the annulus fibrosus

A

collagen fibers of the OUTER lamellae will become SHARPEYs fibers and penetrate EPIPHYSEAL RIMS

collagen fibers of the INNER lamellae will attach to the CARTILAGINOUS ENDPLATE

21
Q

origin for cells of the annulus fibrosus

A

sclerotomites

22
Q

cell type associated with the annulus fibrosus

A

fibroblast and fibrocyte