lalala Flashcards
what is the main principle of infection control in the healthcare setting?
prevent and reduce rates of nosocomial infection
what are the four major areas of infection control?
1) standard precautions (including hand hygiene)
2) isolation precautions
3) environmental cleaning
4) surveillance
what are the indirect consequences of HAIs from a societal perspective?
1) indirect costs to family and caretakers
2) decreased level of productivity from disability
3) decreased trust in healthcare system
4) malpractice costs
5) years of productive life lost to death
6) increased bacterial resistance from increased use of antibiotics
what are three major challenges that have presented in infection control?
1) antimicrobial resistance
2) advances in medicine have led to prolongation of life in immune-compromised hosts
3) there are agents that appear recent in origin
where is MRSA commonly found?
common areas: fitness centers, locker rooms, military living quarters, childcare centers, assisted living facilities, prisons
how does MRSA present?
skin and soft tissue infections
what population is at high risk for VRE infection?
ABX treatment with penicillin/gentamycin, long hospitalization, weakened immune system, ABDOMINAL surgery, invasive devices
KNOW: lies in GI & female genital tract
how does c. diff present?
watery diarrhea, fever, loss of appetite, nausea, abdominal pain/tenderness
complications of c. diff?
pseudomembrane colitis, toxic megacolon, perforation of colon, sepsis, death
risks of developing c. diff?
1) ABX exposure (fluoroquinolones like cipro)
2) proton pump inhibitors
3) GI surgery
4) long hospitalization
5) immunocompromised state
how to treat c. diff?
vancomycin, fecal transplant, metronidazole
what must we keep in mind when trying to protect against c. diff?
alcohol hand gels do NOT kill c. diff spores!
group a. streptococcus is a common HAI; what can it cause?
cellulitis, impetigo, scarlet fever, strep throat, severe infection (bacteremia, toxic shock, necrotizing fascitis)
where do we pick up hospital acquired infections?
1) patient’s own microflora
2) visitor’s microflora
3) hospital environment
4) hospital equipment
5) healthcare workers
what is a surveillance plan?
systematic method of collecting, consolidating, and analyzing data concerning the distribution of determinants of given disease or event, followed by dissemination of that information to those who can improve the outcomes
SO what is the purpose of a surveillance plan?
1) detect outbreaks (via findings on labs & what not)
2) quantify magnitude of problem (datamining based on algorithms)
3) evaluate prevention measures
4) detect changes in healthcare practice
5) facilitate planning
what is targeted surveillance?
looks at a particular type of surgery or procedure or at outcomes related to a particular device
who is responsible for “duty to report” in regards to infectious disease?
1) healthcare providers
2) medical laboratories
3) health care facilities
4) administrations
5) veterinarians
6) health officers
disease reporting is 24/7!
why is TB re-emerging? where is it the worst right now?
multi-drug resistant strains have emerged!
india has 70-80,000 cases of drug-resistant TB each year
what is MDR-TB? what is XDR-TB?
MDR-TB: resistant to at least two first line drug
XDR-TB: also resistance to one of the three second-line drugs
how is ebola transmitted?
contact with infected animal then person-to-person through direct contact with secretions, excretions, blood
why is ebola emerging at such a high rate? why is it hard to treat?
ebola targets the macrophages, and these are the cells that usually elicit the inflammatory response
the early infection of macrophages helps ebola evade the immune system while subsequently spreading through host