Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ObGyn Lecture > Lecture 5 > Flashcards

Lecture 5 Flashcards

1
Q

To be diagnosed with PMS, need 1 symptoms in 5 days pre-menses for how many cycles?

A

3 cycles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When are PMDD symptoms absent?

A

Week post menses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are 4 main somatic symptoms of PMS?

A

Bloating, mastodynia, HA, swelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are three affective symptoms of PMS?

A

Irritable, angry outbursts, moodiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

When are symptoms relieved with PMS?

A

Within 4 days of menses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are some core symptoms of PMDD?

A

Marked depression, marked anxiety, sudden tearfulness/ sadness, increased interpersonal conflicts or persistent & marked anger or irritability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the gold standard for treatment of PMDD?

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are some common meds for PMS?

A

NSAIDs, spironolactone (diuretic), ovulation suppression (OCPs, danazol (blocks all hormones- become male like) GnRH agoinst)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are 3 common SSRIs prescribed for PMDD?

A

Fluoxetine (Prozac), Sertraline (Zoloft), Paraxetine (Paxil)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are some ADRs associated with SSRIs for treatment of PMDD?

A

GI upset, insomnia, sexual dysfunction, wt gain, increased nervousness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is transition time to non-reproductive years prior to menopause?

A

Peri-menopause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the pernmanet cessation of menses. 12 consecutive months w/o menses. Change in follicular phase, luteal phase constant.

A

Menopause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Under what age is premature ovarian failure considered?

A

Under 40 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the primary hormone in menopause?

A

Estrone (E1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What hormone becomes higher with menopause?

A

FSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What does estrone produce?

A

androstenedione & testosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What do bisphosphonates do? (ex- alendronate, risedronate)

A

Inhibit osteoclastic activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What do SERMS (selective estrogen receptor modulator, raloxifene) do?

A

nhibit bone resorption & turnover.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is a a precaution with bisphosphonates?

A

Sit up and don’t eat for at least 30 minutes after

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What can St. John’s wort work to help?

A

Vasomotor symptoms, depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What 2 other supplements can help with vasomotor symptoms of menopause?

A

Soy/isoflavones

Black cohosh

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

If an individual has a uterus, what do they need to be on for hormonal replacement?

A

Progesterone and estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are some contraindications for estrogen therapy?

A

CVA, thromboembolic disease, undiagnosed genital bleeding, biliary tract disorder, known estrogen dependent tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Where are the majority of breast cancers found?

A

In outer, upper quadrants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Higher risk of cancer with Menarche <___ years

A

12 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Menopause > ___ increases risk of breast cancer?

A

55 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

No IUP or IUP > ____ year old increases risk of breast cancer.

A

30 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Why do you preferable do the CBE during the follicular phase?

A

Estrogen dominant cycle, can then compare with mass in other phase

29
Q

Which nodes do you check on a CBE?

A

axillary, epitrochlear, supraclavicular

30
Q

What are the two types of mammography and what is the difference?

A

Screening vs. diagnostic

Screening if for an individual with no mass

31
Q

How many views on done on screening mammogram?

A

4 views (2 on each)

32
Q

What are 2 other things they can do with diagnostic mammography?

A

Compress more, and magnify

33
Q

What are the three types of mastalgia?

A

Cyclic, non-cyclic & extra-mammary

34
Q

What are some Rx for mastalgia?

A

Appropriate bra
weight loss, less caffeine
Vit E
Meds

35
Q

What are some Meds for mastalgia?

A 
OCPS
Depo-provera (progesterone only) 
Bronmocriptine & lisuride
Danazol
SERMS (off-label tamoxifen, raloxifen)
36
Q

What does nonspontaneous, nonbloody & B/L breast discharge indicate?

A

Ductal ectasia (fibrocystic changes)

37
Q

What does purulent nipple discharge indicate?

A

Abscess

38
Q

What meds can cause milky discharge?

A

Tricyclics, OCPs

39
Q

What does bloody, unilateral nipple discharge indicate?

A

Intraductal CA, invasive ductal CA, papilloma (benign)

40
Q

What are some symptoms of a prolactinoma?

A

HA, diplopia, vision change,

41
Q

What are two causes of hyperprolactinemia?

A

Tumor in pituitary or tumor secreting prolactin.

42
Q

If prolactin is elevated what do you do?

A

MRI sella turcica along with visual fields

43
Q

What is dense epithelial & fibroblastic tissue: encapsulated, solid, round, mobile & rubbery often found in adolescents and young women?

A

Fibroadenoma

44
Q

What is inc’d fibrosis w/in lobule along w/compression & distortion epithelium?

A

sclerosing adenosis

45
Q

What is a benign disease that is proliferative w/out atypia. >2 2 cell ayers above basement membrane.

A

Epithelial hyperplasia

46
Q

What is neoadjuvant chemo ?

A

Chemo used to shrink mass before it is removed

47
Q

After initial treatment how often are women seen by gyn?

A

First 2 years- 3-6 months

3rd year and beyond see annually

48
Q

What stage of breast cancer do you: mastectomy or BCT w/ or w/out irradiation

A

Stage 0

49
Q

What stage of breast cancer do you: surgery local control, chemo +/or hormonal

A

Stage IV

50
Q

What stage of breast cancer do you: modified radical or or BCT w/irradiation, axillary node, + chemo, + tamoxifen, + neoadjuvant chemo (try to shrink mass with chemo before you go to remove mass), radiation supraclavicular LN + chest wall & breast (inflammatory type)

A

Stage III

51
Q

What stage of breast cancer do you: mastectomy or BCT w/or w/out irradiation, sentinel node/axillary node, + chemo.

A

Stage I

52
Q

What stage of breast cancer do you: modified radical or or BCT w/irradiation, axillary node, + chemo, + tamoxifen, radiation supraclavicular LN (+ 4 LN) + chest wall?

A

Stage II

53
Q

What is the only med approved by the FDA to treat mastalgia?

A

Damazol

54
Q

What are the two types of carcinoma in situ?

A

Lobular carcinoma in situ (LCIS)

Ductal carinoma in situi (DCIS)

55
Q

What is the single largest risk factor for development cancer?

A

Age- Over 50

56
Q

If ER positive or negative breast cancer easier to treat?

A

ER positive- can attack estrogen receptors

57
Q

Is Her2/neu positive good or bad?

A

Bad

58
Q

What is normal cyclic symptoms associated with ovulation which do not interfere w/ the patient’s daily routine?

A

Molimina

59
Q

What are the most common somatic symptoms that occur with PMS?

A

Abdominal bloating and fatigue

60
Q

What is the term for breast pain and swelling?

A

Mastodynia

61
Q

What is the most common behavioral symptoms of PMS?

A

Emotional lability

62
Q

What is the current theory for what causes of the basis of PMDD?

A

Serotoninergic dysregulation

63
Q

What 2 supplements have shown to decrease symptoms of PMS and PMDD?

A

carbonate and magnesium

64
Q

What are the 4 FDA approved drugs for PMDD?

A

Fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), and drospirenone/ ethinyl estradiol

65
Q

What is the time period during which the changes of menopause occur

A

climacteric

66
Q

The plasma concentration of _______ begin to increase several years in advance of actual menopause.

A

FSH

67
Q

What is usually the first physical manifestation of decreased ovarian function

A

Hot flush

68
Q

What is the only FDA approved med for treating mastalgia?

A

Danazol

ObGyn Lecture (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions