Leprosy

Question 1

What is leprosy basically

Answer 1

chronic granulomatous disease, affecting peripheral nerves and superficial tissues, especially the nasal mucosa

Question 2

Unlike mycobacterium tuberculosis, mycobacterium leprae…

Answer 2

cannot be grown on agar media or in cell culture

Question 3

What are the two major forms of leprosy

Answer 3

tuberculoid and lepromatous

Question 4

How is leprosy transmitted

Answer 4

Through small droplets from nasal secretions of lepromatous patients. Contraction requires prolonged close contact with infected individuals

Question 5

M. Leprae is an obligate intracellular parasite primarilly of?

Answer 5

Macrophages and Schwann cells

Question 6

The Tuberculoid Leprosy

Answer 6

SINGLE skin lesions on the face, limbs, and buttocks. Lesions may not be painful on the limbs but facial lesions generally are. Usually not contagious and the prognosis is good.

Question 7

Lepromatous Leprosy first signs

Answer 7

Edema and rhinitis

Question 8

Lesions in Lepromatous leprosy

Answer 8

On the face, buttocks, and limbs. Damage can be severe with perforation of the nasal septum and collapse of the nose due to cartillage loss, loss of fingers due to neutrophic atrophy, and atrophy of the testicles.

Question 9

Treatment of uberculoid leprosy

Answer 9

A sulfone and Rifampin for 6 mos.

Question 10

Lepromatous Leprosy

Answer 10

Clofazamine + sulfone + Rifampin and treatment has to last for up to 2 years