Flashcards in Lung Cancer Deck (13)
Which lung cancer type tends to appear in the periphery, and which as a central tumour?
A) Small Cell Lung cancer
C) Large cell carcinoma
There can be more than 1 answer.
Small cell lung cancer tends to be a more central tumour.
Adenocarcinoma arise from the bronchial mucosal glands and tends to occur in the periphery. Large cell carcinoma presents as a large peripheral mass on CXR.
Fill in the blanks:
Does adenocarcinoma have an association with smoking?
Adenocarcinoma can originate in scar tissue, and carries a ___ risk of metastatic spread, often to ____ lymph nodes, and ___, producing an ____.
Adenocarcinoma has less association with smoking, but can originate in scar tissue and carries a high risk of metastatic spread, often to mediastinal LN and pleura, causing an effusion.
Dysphagia is especially seen in which cancer type?
B) Large cell carcinoma
C) Small cell lung cancer
C. SCLC, which tends to be a more central tumour.
Hoarse voice is a possible presenting complain. What does it suggest?
Hoarse voice suggests invasion of the recurrent laryngeal nerve.
Squamous cell lung cancer is more common in smokers/non-smokers?
Adenocarcinoma is more common in smokers/non-smokers?
Squamous cell lung cancer is more common in smokers, Adenocarcinoma is more common in non-smokers.
What does having a shoulder pain suggest?
Shoulder pain suggest diaphragm involvement or from brachial plexus involvement.
Finger clubbing is seen especially in which lung cancer type?
Non-SCLC - especially in squamous cell lung cancer
Describe Pancoast syndrome
Pancoast tumours are aka superior sulcus tumours.
Cause chest wall pain, Horner's syndrome (Sympathetic nerve obstruction/interruption) and pain in the T1 dermatomal distribution
Horner's syndrome - miosis, anhydrosis, partial ptosis, enophthalmos.
Which type of lung cancer is the most common cause of SVC obstruction?
Having skin metastases. Which stage of lung cancer is the patient in?
Stage IV - 4.
Metastatic spread everywhere - Stage IV
Metastatic spread to local lymph nodes - Stage III
Complications of lung cancer
1. SVC obstruction - often from SCLC
2. Pleural effusion - often by adenocarcinoma
3. Brain metastases
4. Hypercalcaemia - common in squamous cell lung cancer
5. Cushing's disease or SIADH - common in SCLC
6. Neurological syndromes - Eg. Lambert-Eaton myasthenic syndrome
Describe the difference between squamous cell carcinoma and large cell carcinoma in terms of spread and cancer growth rate.
Squamous cell carcinoma tends to grow slowly, spread locally, and disseminates late.
Large cell carcinoma tends to grow rapidly, and metastasise early. They also tend to be poorly differentiated