Mendelian Inheritance Flashcards Preview

Principles of Disease > Mendelian Inheritance > Flashcards

Flashcards in Mendelian Inheritance Deck (13)
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1
Q

In autosomal dominant, what is the distribution between generations?

A

Every generation affected

2
Q

In autosomal dominant, what is the distribution between sexes?

A

Equal

3
Q

In autosomal dominant, what is the proportion of which sex transmits the disease more?

A

50:50

4
Q

What are the chances of inheriting the disease In autosomal dominant?

A

50%

5
Q

In autosomal recessive, what is the pattern of inheritance between generations?

A

Generations “skipped”

6
Q

In autosomal recessive, what is the distribution between the sexes?

A

Equal

7
Q

What do both parents have to be in order for offspring to be affected?

A

Both carriers or both affected

8
Q

Who is more affected by X linked recessive?

A

Males

9
Q

How is X linked recessive normally transmitted?

A

Through unaffected female carriers

10
Q

What will be the genotype of daughters of affected men in X linked recessive?

A

Carriers unless mother is a carrier/affected

11
Q

In X linked dominant, what pattern of disease is shown?

A

Both sexes affected

12
Q

Who is affected more severely in X linked dominant?

A

Males

13
Q

What will be the genotype of daughters of affected men in X linked dominant?

A

Affected