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Flashcards in Micro Summary: Diseases Deck (90)
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1

Bacteriodes: Bacilus, Prevotella, Porphoryngeus

B. fragilis, P. bivia, P. melaninogenica, P. gingivalis, Abscess, Bacteremia

2

Histotoxic Clostridia: C. perfringens, C. septicum

Wound (gas, anaerobic cellulitis, simple), organ, septicemia, food poisoining

3

C. tetani

Tetanus (CNS, spastic paralysis)

4

C. botulism

Flaccid paralysis, CN dysfunction, double vision, swallowing difficulties, flaccid paralysis, breathing problems, constipation (infants), classical foodborne botulism: contaminated foods, intoxication, infant botulism: most common form of botulism in US, GI tract colonized, infection, adult infant botulism: GI tract colonized, disrupt normal flroa, toxin production, wound botulism: toxin grows in wound, class A select agent: bioterrorism, biowarfare

5

C. difficile

Hospital-acquired infectious diarrhea

6

Campylobacter jejuni

Acute gastroenteritis

7

Haemophilus influenzae

Children: otitis media/sinusitis, epiglottitis, pneumonia, meningitis/bacteremia; Adults: otitis media, sinusitis, LRT

8

Mycoplasma pneumoniae

Persistent cough + erythema multiforme + anemia, thrombotic purpura

9

Escherichia coli

UTIs, neonatal/childhood meningitis

10

Salmonella

Diarrhea (gastroenteritis), enteric fever (typhoid fever)

11

Shigella

Dysentery, GI Symptoms of shigellosis vary from mild diarrhea (no blood) to dysentery (low volume, bloody stool). Shigellosis is usually considered a disease of the colon; it may also involve the ileum? S. sonnei infections usually mildest; S. dysenteriae and S. flexneri more severe

12

Klebsiella

Bloodstream infection, nosocomial pneumonia and urinary tract infection

13

Yersinia pestis

Plague, diarrhea, lymphadenitis, Bubonic: most common, fevers, chills, weakness, headache, painful swollen lymph nodes, Pneumonic: infection of lungs, fever, cough, difficulty breathing, bloody sputum, Septicemic: generalized (bloodstream)

14

Chlamydia trachomatis

Serovars A-K: trachoma, cervicitis, PID, etc., Serovars L1-L3: lymphogranuloma venereum (LGV), Chlamydophila pneumonia: bronchitis & pneumonia, Chlamydophila psittaci: zoonotic, pneumonia (psittacosis)

15

Treponema pallidum

Syphilis

16

Rickettsia rickettsii

"Rocky Mountain Spotted Fever: Rash localized to extremities, Fever, malaise, severe frontal headache, myalgia and vomiting, Abdominal pain, diarrhea, conjunctivitis, mental confusion, meningitis, respiratory difficulties, renal
dysfunction, and/or myocarditis, Lysis of endothelial cells leads to endothelitis"

17

Borrelia burgdorferi

Lyme Disease: Early: bull's eye expanding rash, malaise, fatigue, headache, fever, chills, myalgia, Early-Disseminated: cranial neuropathy, meningitis, radiculoneuropathy, iritis, encrotizing retinis, cardiac dysfunction, Late: oligoarthritis, dermatologic syndromes, neurologic demylination

18

Bacillus anthracis

Cutaneous (95%): exposure of abraded skin to spores, purpitic painless papule, black eschar, enlarged lymph nodes, Inhalational (5%): flu-like, mediastinal widening, hemorrhagic mediastinitis, hemorrhagic meningitis, GI (sporadic): uncooked meat, GI symptoms

19

Francisella tularensis

Tularemia: Ulceroglandular, Pharyngeal, Pneumonic, Oculoglandular, Typhoidal, Glandular

20

Helicobacter pylori

Mild GI inflammation (chronic gastritis), Duodenal or gastric ulcers due to inflammation (ammonia/urease, VacA, CagA), Gastric cancer or lymphoma

21

Enterococcus faecium

Bloodstream infection, endocarditis, UTIs

22

Staphylococcus aureus

Skin & soft tissue disease (*abscess, cellulitis, osteomyelitis, myositis, septic arthritis, impetigo, folliculitis, furuncles, fasciitis), Disseminated disease (*toxic shock syndrome (intoxication), septicemia, endocarditis), Device infections (*central venous catheters, implanted devices, post-surgical infections), CA-MRSA (presence of Panton-Valentine Leukocidin (PVL) gene), Superantigens (food poisoning)

23

Staphylococcus epidermidis

Nosocomial infections w/ IV lines or implanted foreign materials

24

Acinetobacter baumanii

Ventilator associated pneumonia (VAP)

25

Neisseria meningitidis

Meningitis

26

Neisseria gonorrhoeae

M: acute urethritis, urethral dischare, dysuria, most resolve, F: asymptomatic or cervicitis, urethritis, PID (bilateral abdominal pain, tenderness fever), N: conjunctivitis

27

Streptococcus pyogenes

Bacteremia, pneumonia, bone & joint infections, meningitis, endocarditis, Mucosal infections: streptococcal pharyngitis,Pyogenic infections: necrotizing faciitis (attachment from M protein & LTA), Toxigenic: toxic shock syndrome, scarlet fever, Non-suppurative or immunologic: rheumatic fever (inadvertent autoimmunity molecular mimicry), poststreptococcal glomerulonephritis (hematuria/Coca-cola urine, edema, hypertension)

28

Streptococcus pneumoniae

Respiratory Disease: upper (otitis media, sinusitis, conjunctivitis) & lower (CA-pneumonia, death), Disseminated: bacteremia, meningitis, bacterial peritonitis, septic arthritis, osteomyelitis

29

Listeria monocytogenes

Meningitis in babies, bacteremia or meningitis in immunocompromised

30

Legionella pneumophila

Legionnaires' disease & Pontiac fever, cough, fever, diarrhea