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Flashcards in Miscellaneous Deck (3)
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1
Q

ETC Inhibitors (4)

A
  1. Rotenone- Complex I
  2. Cntimycin A- Complex III
  3. Cyanide- Complex IV
  4. Carbon Monoxide- Complex IV

Decreased protein gradient

2
Q

ATP Synthase Inhibitor

A

Oligomycin

Increased protein gradient

3
Q

Uncoupling Agents (MoA and names)

A

MoA: Increase permeability of membrane, decreased proton gradient and increased O2 consumption. Produces heat

  1. 2,4-Dinitrophenol (weight loss drug)
  2. Aspirin
  3. Thermogenin in brown fat