Motor neuron disease Flashcards Preview

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Flashcards in Motor neuron disease Deck (19)
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1
Q

what is motor neuron disease

A

loss of neurons in motor cortex and anterior horn cells

2
Q

what age group and prognosis does MND have

A

about 60

2-4 years

3
Q

is there sensory loss in MND

A

no

4
Q

ALS age group

A

60

5
Q

What is there loss of in ALS

A

neurons in voluntary muscles

6
Q

UMN signs in ALS

A

upgoing plantar

7
Q

LMN signs in ALS - 2

A

wasting and fasiculations

8
Q

ALS symptoms - 2

A

stiff muscles

twitching

9
Q

Progressive bulbar palsy affects which CN

A

9-12

10
Q

what does Progressive bulbar palsy affect - 3

A

speech
swallowing
chewing

11
Q

symptoms of Progressive bulbar palsy - 3

A

fatigue
stress
pain

12
Q

progressive muscular atrophy symptoms - 2

A

fasiculations

muscle weakness

13
Q

is progressive muscular atrophy UMN or LMN

A

LMN

14
Q

which muscles group does progressive muscular atrophy affect - 1
- voluntary or involuntary muscle group?

A

distal muscle groups

voluntary muscles

15
Q

where are the lesions in primary lateral sclerosis

A

anterior horn leisons

16
Q

what happens in primary lateral sclerosis

A

progressive voluntary muscle weakness

17
Q

is primary lateral sclerosis UMN or LMN

A

UMN

18
Q

what is a symptom of primary lateral sclerosis

A

spastic leg weakness

19
Q

treatment for MND (3)

  • prolonging life
  • drooling
  • dysphagia
A
  1. antiglutamatergic - prolongs life about 3 months
  2. drooling - propantheine, amitriptalyine
  3. dysphagia - blend food, HGT