Motor Neuron Disease Flashcards Preview

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Flashcards in Motor Neuron Disease Deck (25):
1

what is MND

untreatable rapidly progressive neurodegenerative condition

2

sensory symptoms are present in MND, true or false

False, it is MOTOR neuron disease

3

what % of cases are sporadic and familial

90% sporadic
10% familial

4

what is the peak age for MND

50-75 yo

5

which classification of MND is most commonly used

UMN vs LMN

6

what does PLS stand for

primary lateral sclerosis

7

what does ALS stand for

amyotrophic lateral sclerosis

8

what does PMA stand for

progressive muscular atrophy

9

what does FTD stand for

frontotemporal dementia

10

what does PBP stand for

progressive bulbar palsy

11

PLS is UMN/LMN

UMN

12

ALS is UMN/LMN

it is mixed

13

PMA is UMN/LMN

LMN

14

what is the most common type of MND

ALS

15

UMN disease features

hypertonia
hyper reflexia
plantar reflex
spasticity
jaw jerk reflex

16

LMN disease features

hypotonia
hypo/absent reflexes
muscle wasting
muscle weakness
fasciculations
floppy

17

cognitive impairment is a feature of MND, true or false

true

18

what is split hand syndrome and what is a pattern of

preferential wasting of thenar group muscles seen in ALS

19

describe bulbar variant of MND

always generalises into ALS
breathing, speech, swallowing problems

20

how can MND present

in any way - there is no classical pattern
mixed UMN and LMN disease
dementia
frontal
bulbar presentation
cachectic
tongue fasciculation
spinal dysfunction

21

MND is a diagnosis of exclusion, true or false

true

22

what other conditions should be excluded

MS
Gullain Barré
multifocal motor neuropathy - MMN
Kennedy's
inclusion body myositis
radiculopathy

23

supportive management of MND

healthcare team
communication needs eg voice banking
nutrition - dietician, gastrostomy
ventilation

24

medical management of MND

riluzole
many side effects
taken as a last resort

25

what are respiratory red flags

SOB
orthopnoea
chest infection
disturbed sleep
nightmares
daytime sleepiness