Movement disorders

Question 1

Neurofibrillary tangles are seen in

Answer 1

alzheimers

Question 2

Alzheimer’s chemical changes

Answer 2

↓ ACh

Question 3

Neurofibrillary tangles are

Answer 3

intracellular, hyperphosphorylated tau protein

Question 4

Physiologic tremors are?

Answer 4

anxiety, thyroid, caffeine

Question 5

hereditary motor and sensory neuropathy is aka?

Answer 5

Charcot-Marie-Tooth

disease

Question 6

Moderate form has cleft lip/palate, most severe

form results in cyclopia. Seen in Patau syndrome and fetal alcohol syndrome

Answer 6

Holoprosencephaly Failure of left and right hemispheres to separate; usually occurs during weeks 5–6.

Question 7

Raphe nucleus makes

Answer 7

Serotonin

Question 8

Locus ceruleus makes?

Answer 8

NorEpi

Question 9

Nucleus accumbens makes?

Answer 9

GABA

Question 10

Ventral tegmentum makes

Answer 10

Dopamine

Question 11

Basal nucleus of Meynert makes

Answer 11

Acetylcholine

Question 12

Pk chemicals

Answer 12

↑ AcH and serotonin

↓ Da

Question 13

Hypothalamus does what?

Answer 13

The hypothalamus wears TAN HATS—
Thirst and water balance, Adenohypophysis control
(regulates anterior pituitary), Neurohypophysis releases hormones produced in the hypothalamus,
Hunger
Autonomic regulation, Temperature regulation, Sexual urges.

Question 14

If you zap your ventromedial hypothalmus area, you ?

Answer 14

get fat in your MEDdle

Question 15

If you zap your lateral hypothalmus area, you ?

Answer 15

shrink skinny

Question 16

Limbic system does

Answer 16

Responsible for Feeding, Fleeing, Fighting, Feeling, and Sex….

Question 17

What is 2nd line for essential treatment

Answer 17

primidone

benzos can too

Question 18

Symptoms of altered activity

Mesocortical

Answer 18

↓ activity –> Ž “negative” symptoms (flat affect)

*Dopaminergic
pathways

Question 19

Mesolimbic- Symptoms of altered activity

Answer 19

↑ activity –> Ž “positive” symptoms (eg, delusions,
hallucinations)

*Dopaminergic
pathways

Question 20

Symptoms of altered activity

Tuberoinfundibular

Answer 20

if ↓

more prolacin,less sexy time and biggerboobs (or new boobs!)

Question 21

Major dopaminergic pathway in brain.

Significantly affected by movement disorders

Answer 21

Nigrostriatal

Question 22

Dystonia is?

Answer 22

Sustained, involuntary muscle contractions

Question 23

composed of α-synuclein—intracellular eosinophilic inclusions

Answer 23

Lewy bodies

seen in Pk

Question 24

wernike is in the____ lobe

Answer 24

temporal

Wernicke area in superior temporal
gyrus of temporal lobe.

Question 25

Broca area in ____ of frontal lobe.

Answer 25

inferior frontal gyrus

Question 26

Describe wernicke

Answer 26

Wernicke is Wordy but makes no sense.

Question 27

Wernicke problems come in a CAN of beer

Answer 27

Confusion, Ataxia, Nystagmus

confusion, ophthalmoplegia, ataxia; memory loss
(anterograde and retrograde amnesia), confabulation, personality changes.

Question 28

Intention tremor, limb ataxia, loss of balance

Answer 28

damage to cerebellum Ž–> ipsilateral deficits;

fall toward side of lesion.

Question 29

hemibasilus lesionlocation

Answer 29

Subthalamic nucleus

Question 30

uncommon brain disorder that causes serious problems with walking, balance and eye movements.

Answer 30

supranuclear palsy