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Flashcards in MS Deck (11)
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1
Q

What is MS? 3 points

A
  1. T cell mediated, autoimmune
  2. demyelinated plaques
  3. lesions in CNS separated by time and space
2
Q

MS presentation

A
unilateral optic neuritis
diplopia
ataxia
numbness/tingling
headaches
UMN
3
Q

MS - Lhermittes sign

A

shock down spine

4
Q

MS - Uthoff

A

increase in body temperature exacerbates symptoms (nerve deadness)

5
Q

MS investigations

A

-ABCDE
-Blood- FBC, MCV, WBC, ESR, UE –> check infective markers
-MRI - plaque leisons in white matter in the brain
- Bone profiling - Ca and Mg
Autoimmune screen - ANA and ANCA
Lumbar puncture - oligoclonal bands, look in CSF for pleocytosis
- EEG

6
Q

differential diagnosis for MS

A
blood in eye
retinal detachment
vitral hemmorhage
occlusion
optic nerve
7
Q

MS management - 8 points

some say dont play there cause of predators

A
  1. stabilise
  2. steroids- prednisolone or methylpred (IV)
  3. dexamethasone
  4. plasmaphoresis
  5. tysabin
  6. carbamezapine
  7. OT
  8. physio
8
Q

MS can cause 3 things

A
  1. pseudo bulbar palsy
  2. urinary incontinence
  3. muscle spasms
9
Q

pseudo bulbar

  • what is it
  • where is affect
  • treatment
A

no control on facial movements
UMN
- give steriods

10
Q

urinary incontinence

  • what from
  • what to give
A

spinal damage

cholinergics, continence nurse

11
Q

muslce spasms type (1) and treatment (2)

A

tonic clonic

baclofen, dizaepam