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Flashcards in MTB 1 Deck (38)
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1
Q

Best initial test for Breast Cancer

A

FNA BX

2
Q

Breast cancer findings on PE

A

Hard to touch
Retraction of nipple
Painless

3
Q

How to test for estrogen/progesterone/HER2/neu receptors?

A

Core needle Bx - more deforming

4
Q

Most accurate Dx test for breast cancer

A

Open BX - frozen section in OR w immediate resection

5
Q

When do we screen w mammography?

A

Start at 50 yoa

6
Q

When do we do US in breast cancer

A

Indeterminant mass lesions
Painful
Varies w menstruation
- US tells cysts v solid lesions

7
Q

When do we do PET in breast cancer

A

To determine content of LNs not accessible by Bx

8
Q

How does cancer present on PET

A

Cancer increases uptake on PET

9
Q

BRCA ass’d with?

A

Breast ca

Ovarian ca

10
Q

When do we Bx Sentinel Node

A

Routinely in all pts when lumpectomy or masectomy is done

11
Q

When is ER and PR testing done

A

Routinely in all pts

12
Q

Why is radiation important in breast cancer TX

A

Indispensible in preventing recurrences

13
Q

What AEs do aromatase inhibitors cause

A

Osteoporosis

14
Q

Trastuzumab
MOA
Benefit

A

Anti-Her2/neu Abs

Decreases risk of recurrent dz

15
Q

When do we do adjuvant chemo in breast cancer

A

Lesions > 1cm

Positive axillary LN

16
Q

DOC when multiple first degree relatives w breast cancer and why

A

Tamoxifen

Lowers risk of breast cancer

17
Q

Best initial test Prostate Cancer

A

BX

18
Q

Most accurate test Prostate Cancer

A

BX

19
Q

TX for Prostate Cancer

A

Surgery - prostatectomy

20
Q

AEs of Prostatecomy

A

ED

Urinary Incontinence

21
Q

What does Gleason Grading measure

A

Aggressiveness

Malignant potential

22
Q

Management that is WRONG in prostate cancer

A

Screening imaging
Lumpectomy
Chemo

23
Q

High PSA + Palpable mass = next step?

A

BX the mass

24
Q

High PSA + No Palpable mass = next step?

A

Transrectal US

  • if Mass seen = BX
  • if no mass seen = multiple blind BX’s
25
Q

When do we not do surgery in Lung Cancer

A

Bilateral
Malignant pleural effusion
Heart, Carina, Aorta, Vena Cava involved

26
Q

Which cancer is unresectable in 95%

A

Small cell - mets outside lung

27
Q

What kind of cancer is Lip cancer?
Causes
Presentation

A

SQCC - invasive cords of squamous cells w keratin pearls
Sun exposure
Vermillion zone of lower lip
non-healing

28
Q

Ovarian Cancer presentation

A

Woman > 50 yoa
Increasing abdominal girth
Weight loss

29
Q

Ovarian Cancer
Initial test
Accurate test

A

Initial Test: US or CT

Accurate: Bx

30
Q

Tx for Ovarian Cancer

A

Resection - all visible tumor and pelvic organs

Chemo

31
Q

Presentation of Testicular Cancer

A

Painless Lump in scrotum

Does NOT transilluminate

32
Q

Test for Testicular Cancer

A

Remove whole testicle w inguinal orchiectomy

Never needle Bx

33
Q

Which testicular cancers secrete AFP

A

Nonseminomatous cancers

34
Q

TX for Testicular Cancer

A
  1. Orchiectomy
  2. Radiation for Local
    Chemo for widespread
35
Q

How does Testicular Cancer Metastasize

A

Thru Lymphatics in retroperitoneum and moves into chest

36
Q

What is TX for Brain mets w solitary lesion

A

Surgical resection + Whole brain Radiation

37
Q

What is TX for Brain mets w multiple lesions

A

Palliative
Whole Brain Radiation
Glucocorticoids

38
Q

Management of Advanced cervical cancer

A

Hysterectomy