Mutation and Genetic Code Flashcards Preview

Genetics (David Oh) > Mutation and Genetic Code > Flashcards

Flashcards in Mutation and Genetic Code Deck (7)
Loading flashcards...
1
Q

ORF

A

open reading frame - portion of dna molecule that, when translated to amino acids, contains no stop codons

2
Q

missense mutation

A

non syn change that alters amino acid identity

3
Q

frameshift mutation

A

insertion or deletion (indel) of base pairs, to shift the reading frame and
eventually produce a premature stop codon

4
Q

nonsense mutation

A

Converts a codon encoding an amino acid to a stop codon

5
Q

how do cells destroy mRNAs with premature stop codons?

A

nonsense-mediated decay. however transcripts with the nonsense codons in the last exon are spared

6
Q

are human gene names italicized or not?

A

yes

7
Q

are human protein names italicized or not?

A

no