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Flashcards in Nephritic Case Studies Deck (10)
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1
Q

LN Class 1 and Class 2

LM/IF/EM

A

1- normal, mesangial, mesangial

2- mesangial all 3

2
Q

LN Class 3 and 4

LM/IF/EM

A

3- focal prol, mesang cap loop, mes, sudendo

4- diffuse prolif, all the rest same

3
Q

LN Class 5 and 6

LM/IF/EM

A

5- thick GBM, Cap loop. Subepi, mes

6- GS,TA,IF/ +-/chronic changes

4
Q

LN Class 1 and Class 2 symptoms

A

1- normal UA, no/min proteinuria, normal creat

2- micro hematuria/proteinuria, no HTN

5
Q

LN Class 3 and 4 symptoms

A

Both= hematuria, proteinuria (nephrotic), HTN, dec GFR

6
Q

LN Class 5 and 6 symptoms

A

5- Nephrotic proteinuria, MH, HTN, norm creatinine

6- proteinuria/hematuria, dec GFR, ESRD

7
Q

Nephritic syndrome

A

HTN, hematuria, proteinurai

8
Q

ANCA Ab directed to antigens

CANCA
PANCA

A

on cytosol of neutrophil

C- bind ag in cytoplasm
P- bind ag in perinuclear region

9
Q

IgA nephropathy & complement

A

Alternative pathway in kidney

Serum levels are normal

10
Q

IgA and URI

Deposit where

A

After viral URI, IGA surge in production, including galactose deficient

Deposited in mesangium