Neurology - MS Flashcards Preview

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Flashcards in Neurology - MS Deck (7)
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1
Q

What is the pathology of MS?

A

autoimmune demyelination

Immune response mediated by T cells lead to inflammatory attack with demyelination of white matter of spinal cord

2
Q

What are the signs of MS?

A

pain, sensation problems, optic neuritis, weakness (irregular), how shower worsens symptoms

3
Q

How would you test for MS?

A

CT/MRI, LP (oligocordial bands), NCS

4
Q

How would you treat MS?

A

steroids, DMARDs (IFN-B prevents immune activation, natalizumab modifies lymphocyte trafficking)
stem cell transplant

5
Q

What is the treatment for MS?

A
steroids in relapse 
DMARDs - interferon
monoclonal antibodies - alemtuzumab, natalizumab 
tecfidera - dimethyl fumerate
stem cell transplant
6
Q

Name 3 patient speak phrases of MS

A
got worse in the shower 
tripping 
blurred vision 
blurred vision 
electric shock feeling down spine
7
Q

What is the criteria to diagnose MS?

A

2 or more CNS lesions disseminated in time and space

- exclude other conditions