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Skin > Norton Part 7 > Flashcards

Norton Part 7 Flashcards

1
Q

what is psoriasis

A

accelerated proliferation of skin cells resulting in scaling

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2
Q

psoriasis occurs at what age

A

any but average is 35 years old

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3
Q

psoriasis can impact what about the patient in every day

A

quality of life and self-esteem impacts can be enormous

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4
Q

normally it takes 28 days for keratinocytes to move from stratum basal to shedding, in psoriasis this is how long

A

3-4 days

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5
Q

well-demarcated, erythematous plaques and papule with silver scaling is seen in what

A

psoriasis

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6
Q

what is Auspitz’s sign

A

pinpoint bleeding on removal of scale

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7
Q

auspitz’s sign is seen in what

A

psoriasis

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8
Q

what is the Koebner phenomenon

A

trauma to the skin and stress can cause exacerbation of lesions

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9
Q

what histological features are seen in psoriasis

A

downward elongation of rete ridges
thinning of overlying stratum granulosum with parakeratosis above
aggregates of neutrophils with surrounding spongiosis
capillaries in dermal papillae are brought close to the surface

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10
Q

erythrodermic psoriasis involves what

A

entire skin

very serious

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11
Q

Guttate psoriasis involves what

A

scattered, dry-like, pink, scaly plaques

may follow strep infections

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12
Q

pustular psoriasis is what

A

pustules on erythematous skin on palms/soles or generalized

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13
Q

50% of patients with psoriasis what is involved

A

nails
oil spotting- focal brown discoloration of nail plate
onycholysis- distal separation of plate from bed
subungual hyperkeratosis
pitting

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14
Q

pencil in cup deformity is seen in what

A

psoriatic arthritis

due to erosions

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15
Q

what should one not give patients with psoriasis

A

oral steroids

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16
Q

seborrheic dermatitis (“cradle cap” and dandruff) is what type of disorder

A

chronic inflammatory process affecting areas rich in sebaceous glands

17
Q

seborrheic dermatitis peaks when

A

infacny and adulthood

18
Q

what causes seborrheic dermatitis

A

yeast Malassezia furfur (normal in skin)

19
Q

seborrheic dermatitis

A 
scalp
ears
eyebrows
nasolabial folds
chest
20
Q

seborrheic demratitis is more common in people with what

A

parkinsons and HIV

21
Q

what is seen in seborrheic dermatits

A

yellow, greasy, scaly patches with surrounding erythema

22
Q

Puritic, purple, polygonal, planar papules, plaques are seen in what

A

lichen planus

23
Q

what type of history would one expect to see in lichen planus

A

severe itching

24
Q

what are Wickham’s striae and what are they associated with

A

fine, reticulated, white lines

seen in lichen planus

25
Q

the koebner phenomenon is seen in what conditions

A

psoriasis

lichen planus

26
Q

what virus may be associated with lichen planus

A

hepatitis C

27
Q

what histological features are seen in lichen planus

A

interface dermatitis- dense, continuous infiltrate of lymphocytes along the dermoepidermal junction
civatte bodies- incorporation of necrotic basal keratinocytes into inflamed papillary dermis
dermoepidermal interface changed to a more angulated zigzag (saw-toothing)
associated with degeneration and necrosis basal keratinocytes

28
Q

where is lichen planus most commonly found

A

wrists and ankles

mucus membrane involvement is common

29
Q

lichen Plans is usually self limited, how long until it resolves?

A

1-2 years after onset

30
Q

systemic lupus erythematous is what type of disease

A

autoimmune involving connective tissues and blood vessels

due to immune complex deposition (Type III)

31
Q

SLE is more common in what people

A

African Americans
Females to male (9:1)
30-40 years old

32
Q

what to patients with SLE present with

A 
skin lesions that are exacerbated in the sun
fatigue
fever
weight loss
malaise
arthralgias
CNS symptoms
33
Q

what is a malar rash

A

“butterfly rash” erythematous, confluent, macular eruption with clear borders
spares nasolabial folds

34
Q

the malar rash (butterfly rash) is associated with what

A

SLE

35
Q

what systemic effects are seen in lupus

A 
oral ulcers
renal disease
pericarditis
pneumonitis
peritonitis
hepatosplenomegaly
myopathy
neuropathy
lymphadenopathy
seizures
36
Q

SLE gives what results on RPR and VDRL

A

false positive

37
Q

what histological features are seen in SLE

A

lichenoid interface dermatitis
epidermal atrophy
thickening of basal membrane

Skin (12 decks)

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