amine donor for IMP–>XMP–>GMP
glutamine
amine donor for IMP–>AMP
aspartate
enyzme to create PRPP
PRPP synthetase
redox cofacto for dehydroxylaing #2 carbon of ribose
Thioredoxin
defect in adenosine deaminse
SCID
defect in HGPRT
lesch nyan
defect in purine nucleoside phosphorylase
CID
which can be directly phospgoyrlated in purine salvage? Adenine, Guanine or Hypoxanthine?
Adenine
self injusry , hyperuricemina, MR, dystonia, renal failure, sx of?
Lesch nyan
low lymphocytes, skeletal abnormalites, sx of?
SCID
neurologic symptoms, low T cell, FFF, chronic infection all sx of?
CID
purine degradation lead to buildup of this in gout
uric acid
treats gout by inhibiting xanthine oxidase
alloprinol
needed for pyrimidine RNA synthesis
UTP and CTP
needed for pyrmindine DNA synthesis
dCTP, DTTP
needed for purine synthesis for RNA
GTP and ATP
needed for purine synthesis for DNA
dGTP and dATP