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Medicine, oncology > Palliative medicine > Flashcards

Palliative medicine Flashcards

1
Q

Most common cause of nausea/comiting?

A

Chemotherapy

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2
Q

Classification of N/V?

A

Acute: less than 24 hours after chemotherapy. (serotonin)
Delayed: more than 24 hours

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3
Q

RFs for N/V?

A

Female
young age
motion sickness
COMBINATION chemotherapy

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4
Q

What decreases risk for N/V?

A

Alcohol consumption

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5
Q

Which antineoplastic agents have HIGH risk of N/V?

A

Cisplatin
Cyclophosphamide
Dacarbazine

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6
Q

How to treat high risk N/V?

A

Use several anti-emetic agents at the same time

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7
Q

Management of N/V?

A

PREVENTION with antiemetics:

  • Ondansetron
  • metoclopramdie
  • dexamethasone
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8
Q

Criteria for febrile neutropenia?

A

Temp above 38,5

Neutrophils

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9
Q

What is most concerning complication of chemotx?

A

Febrile neutropenia

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10
Q

When does febrile neutropenia show an even worse prognosis?

A

When proven bacteremia

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11
Q

What is name of risk score in febrile neutropenia?

A

MASCC

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12
Q

Which MASCC score shows low risk of complication?

A

score over 21

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13
Q

Treatment if low risk of febrile neutropenia?

A

give oral ABs (ciprofloxacin, amoxicillin)

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14
Q

Treatment if high risk of febrile neutropenia?

A

give broad-spectrum ABs (carbopenems)

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15
Q

How high is mortality if MASCC score is beklow 15?

A

36 %

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16
Q

Which therapeutic treatment used in febrile neutropenia?

A

G-SCF (Filgrastim!)

17
Q

What is filgrastim?

A

G-CSF, used in febrile neutropenia

18
Q

how is pain classified?

A

Nociceptive: somatic and visceral
Neuropathic: central and peripheral

19
Q

In which cancer is VISCERAL pain commonly seen?

A

Pancreatic ca!!!!

20
Q

Tx of allodynia?

A

Amytryptiline (TCA)
Gabapentin (Neurontin)

+ non-opioids and strong-opioids

21
Q

Which ca give bone mets?

A

Lung
Prostate
Breast

22
Q

Examples of weak opioids?

A

Tramadol

Codeine

23
Q

Examples of strong opioids?

A

Fentanyl

Morphine

24
Q

What anti-neoplastic tx may cause dyspnea?

A

Lung resection
Bleomycin
Radiotx

25
Q

Tx of dyspnea?

A 
Opiods
positioning
fresh air
Benzo/SSRIs
Bronchodilator, steroids, ABs
26
Q

Whish respiratory symptoms is a POOR prognostic factor?

A

Recurrent pleural effusion!!!

27
Q

Criteria used in pleural effusion?

A

Light’s criteria

28
Q

Tx for cough?

A

Morphine
Codeine
Dihydrocodeine

29
Q

What is the cause of death rattle?

A

Accumulation of airway secretions –> movement of secretions in hypopharynx

30
Q

What does death rattle predict?

A

DEATH (STRONG predictor!)

31
Q

Management of death rattle?

A

Positioning
ANticholinergics
Fluid restriction

Medicine, oncology (15 decks)

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