Pancreas, Gallbladder, Liver Pathology

Question 1

Mild vs severe pancreatitis

Answer 1

mild: edema
severe: hemorrhage into interstitial area

Question 2

Elastases cause damage to what structures

Answer 2

blood vessels

Question 3

Early vs late chronic pancreatitis damaging structures

Answer 3

early: exocrine acinar cell injury
late: endocrine cell injury
(both irreversible)

Question 4

What is the difference between damaging parenchyma cells and stromal cells?

Answer 4

if stromal damage –> fibrosis

if just parenchyma, may regenerate itself

Question 5

Type I chronic pancreatitis

Answer 5

IgG4-producing plasma cells

can form nodules

Question 6

Relatively common pancreatic lesions

Answer 6

pseudocysts
due to acute pancreatitis or trauma
75% of cysts in pancreas

Question 7

Serous (microcystic) cystadenoma

Answer 7

rare, benign neoplasm of pancreas
cuboidal cells surrounding small cysts
filled with serous fluid

Question 8

Mucinous cystic adenoma/adenocarcinoma

Answer 8

almost always in women

several, large, mucus-filled cysts

Question 9

Pancreatic exocrine carcinoma

Answer 9

ductal adenocarcinomas

Question 10

Pancreatic carcinoma most often occurs where in the pancreas

Answer 10

head, not well circumscribed

Question 11

Neuroendocrine tumors of pancreas most often occur where

Answer 11

body/tail of pancreas, often well circumscribed

Question 12

Cholangiocarcinoma

Answer 12

carcinoma of bile ducts

differentiated by location on biliary tree