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Flashcards in Path I final - matching Deck (79)
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1
Q

Crystal shape/birefringence in Monosodium Urate?

A

Needle or rod shaped, strong birefringence

2
Q

Crystal shape/birefringence in Ca pyrophosphate dihydrate?

A

Rhomboid or rod shaped, weak birefringence

3
Q

Crystal shape/birefringence in Ca oxalate?

A

Bipyramidal shaped, weak or strong birefringence

4
Q

Crystal shape/birefringence in Basic Ca phosphate?

A

shiny/coin-like/irregular shaped, NOT birefringent

5
Q

What etiologic category are achondroplasias in?

A

Abnormal receptors

6
Q

What etiologic categories is reactive arthritis in?

A

STDs and dysenteric

7
Q

What etiologic category is Myasthenia Gravis in?

A

Thyoma

8
Q

What etiologic category is Lambert-eaton Myasthenic Syndrome in?

A

Decreased Ach release

9
Q

What etiologic category is osteomalacia/rickets in?

A

Mineral homeostasis

10
Q

what etiologic category is hyperparathyroidism in?

A

Mineral homeostasis

11
Q

What etiologic category is Paget’s disease in?

A

Osteoclast

12
Q

What etiologic category is Osteopetrosis in?

A

Osteoclast

13
Q

What is Reactive arthritis aka?

A

Reiter’s

14
Q

What is systemic sclerosis aka?

A

scleroderma

15
Q

What is osteopetrosis aka?

A

Alber’s-schonberg disease, marble bone disease

16
Q

What is Epiphysitis of the calcaneus aka?

A

Sever’s disease

17
Q

What is neurogenic arthropathy aka?

A

Charcot’s joints

18
Q

What is morton’s neuroma aka?

A

Metatarsalgia

19
Q

What is Anterior achilles tendon bursitis aka?

A

Albert’s disease, retromalleolar bursitis

20
Q

What is monosodium urate crystal deposition disease aka?

A

Gout

21
Q

What is calcium phosphate dihydrate crystal deposition disease aka?

A

pseudogout

22
Q

What is Paget’s disease aka?

A

Osteitis deformans

23
Q

What is Cushing’s syndrome caused by? (cancer type)

A

small-cell carcinoma of lung

24
Q

What is SIADH caused by? (cancer type)

A

small cell carcinoma of lung and intracranial neoplasms

25
Q

What is hypercalcemia caused by? (cancer type)

A

squamous cell carcinoma of lung, breast carcinoma, renal cell carcinoma

26
Q

What is venous thrombosis caused by? (cancer type)

A

pancreatic carcinoma

27
Q

What is polycythemia caused by? (cancer type)

A

renal cell carcinoma and hemangioblastoma

28
Q

What is myasthenia gravis caused by? (cancer type)

A

thymoma, small cell lung carcinoma

29
Q

What is Lambert-Eaton syndrom caused by? (cancer type)

A

small cell carcinoma of lung

30
Q

What is gout/urate neuropathy caused by? (cancer type)

A

leukemias and lymphomas

31
Q

What is the cause of paraneoplastic Cushing’s syndrome?

A

ACTH

32
Q

What is the cause of paraneoplastic SIADH?

A

ADH

33
Q

What is the cause of paraneoplastic hypercalcemia?

A

PTH-like polypeptide, TGF-alpha

34
Q

What is the cause of paraneoplastic venous thrombosis?

A

thromboplastin

35
Q

What is the cause of paraneoplastic polycythemia?

A

erythropoietin

36
Q

What is the cause of paraneoplastic myasthenia gravis?

A

Ab to ach receptor at NMJ

37
Q

What is the cause of paraneoplastic Lambert-Eaton syndrome?

A

Ab to pre-synaptic Ca channels in nerve axons

38
Q

What is the cause of paraneoplastic Gout/urate neuropathy?

A

Hyperuricemia due to excess nucleic acid turnover

39
Q

What disorder is antinuclear antibody (ANA) associated with?

A

SLE (not exclusive)

40
Q

What disorder are anti-dsDNA and anti-Smith associated with?

A

specific for SLE

41
Q

What disorder is antihistone associated with?

A

Drug-induced lupus

42
Q

What disorder is anti-IgG (rheumatoid factor) associated with?

A

Rheumatoid arthritis

43
Q

What disorder is anticentromere associated with?

A

scleroderma (CREST)

44
Q

What disorder is anti-Scl-70 associated with?

A

Scleroderma (diffuse)

45
Q

What disorder is anti-Jo-1 associated with?

A

Polymyositis, dermatomyositis

46
Q

What disorder is anti-SS-A (anti-Ro) associated with?

A

Sjogrens syndrome

47
Q

What disorder is anti-SS-B (anti-La) associated with?

A

Sjogrens syndrome

48
Q

What disorder is anti-U1 RNP (ribonucleoprotein) associated with?

A

Mixed Connective Tissue Disease (MCTD)

49
Q

What disorder is anti-CCP antibody associated with?

A

Rheumatoid arthritis

50
Q

Which type of hypersensitivty disorder is hay fever (allergic rhinitis)?

A

Type 1 (anaphylactic)

51
Q

Which type of hypersensitivty disorder is asthma?

A

Type 1 (anaphylactic)

52
Q

Which type of hypersensitivty disorder is atopic dermatitis?

A

Type 1 (anaphylactic)

53
Q

Which type of hypersensitivty disorder is anaphylactic shock?

A

Type 1 (anaphylactic)

54
Q

Which type of hypersensitivty disorder is hemolytic anemia?

A

Type 2 (cytotoxic antibody)

55
Q

Which type of hypersensitivty disorder is goodpasture syndrome?

A

Type 2 (cytotoxic antibody)

56
Q

Which type of hypersensitivty disorder is Graves disease?

A

Type 2 (cytotoxic antibody)

57
Q

Which type of hypersensitivty disorder is Myasthenia gravis?

A

Type 2 (cytotoxic antibody)

58
Q

Which type of hypersensitivty disorder is idiopathic thrombocytopenic purpura?

A

Type 2 (cytotoxic antibody)

59
Q

Which type of hypersensitivty disorder is erythroblastosis fetalis?

A

Type 2 (cytotoxic antibody)

60
Q

Which type of hypersensitivty disorder is rheumatic fever?

A

Type 2 (cytotoxic antibody)

61
Q

Which type of hypersensitivty disorder is bullous pemphigoid?

A

Type 2 (cytotoxic antibody)

62
Q

Which type of hypersensitivty disorder is serum sickness?

A

Type 3 (immune complex)

63
Q

Which type of hypersensitivty disorder is poststreptococcal glomerulonephritis?

A

Type 3 (immune complex)

64
Q

Which type of hypersensitivty disorder is arthus reaction?

A

Type 3 (immune complex)

65
Q

Which type of hypersensitivty disorder is polyarteritis nodosa?

A

Type 3 (immune complex)

66
Q

Which type of hypersensitivty disorder is systemic lupus erythematosus?

A

Type 3 (immune complex)

67
Q

Which type of hypersensitivty disorder is rheumatoid arthritis?

A

Type 3 (immune complex)

68
Q

Which type of hypersensitivty disorder is hypersensitivity pneumonitis?

A

Type 3 (immune complex)

69
Q

Which type of hypersensitivty disorder is contact dermatitis?

A

Type 4 (delayed)

70
Q

Which type of hypersensitivty disorder is chronic transplant rejection?

A

Type 4 (delayed)

71
Q

Which type of hypersensitivty disorder is Graft-vs-host disease?

A

Type 4 (delayed)

72
Q

Which type of hypersensitivty disorder is reaction to tumors?

A

Type 4 (delayed)

73
Q

Which type of hypersensitivty disorder are infections with mycobacterium tuberculosis, mycobacterium leptae, fungi?

A

Type 4 (delayed)

74
Q

Which type of hypersensitivty disorder is sarcoidosis?

A

Type 4 (delayed)

75
Q

Which type of hypersensitivty disorder is type 1 DM?

A

Type 4 (delayed)

76
Q

Which type of hypersensitivty disorder is multiple sclerosis?

A

Type 4 (delayed)

77
Q

Which type of hypersensitivty disorder is Guillain-Barre syndrome?

A

Type 4 (delayed)

78
Q

Which type of hypersensitivty disorder is Hashimotos thyroiditis?

A

Type 4 (delayed)

79
Q

Which type of hypersensitivty disorder is PPD?

A

Type 4 (delayed)