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Flashcards in Pathology Deck (5)
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1
Q

Components of the filtration barrier - 3

A
  1. Fenestrated endothelial layer - prevents filtration of blood cells and platelets
  2. Basal lamina - highly negatively charged; prevents filtration of molecules 60-70k Daltons and larger
  3. Filtration slits between podocytes
2
Q

2 cell types of collecting tubule/duct

A

Principal Cell

Intercalated Cell

3
Q

Principal Cell - Function

A

Reabsorbs Na+ from the collecting tubule lumen in exchange for K+ secretion

4
Q

Intercalated Cell

A

Secrete H+ and reabsorb HCO3-

5
Q

Juxtaglomerular Complex (JGA/JXA)

A

Modified smooth muscle cells in the wall of the afferent arteriole; secrete renin