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Medicine, oncology > Practical aspects in oncology > Flashcards

Practical aspects in oncology Flashcards

1
Q

Name systemic treatments

A

Chemotx
Hormonal tx
Targeted tx

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2
Q

What is a clinical oncologist?

A

Chemo + radio

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3
Q

What is a medical oncologist?

A

Chemo

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4
Q

3 questions in oncology?

A

Is it cancer? - biopsy
WHat type of cancer? - imaging, biopsy
WHat is intention of tx? - curative, palliative

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5
Q

What is adjuvant tx?

A

Given after surgery to maximize chance for cure

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6
Q

What is neoadjuvant tx?

A

given before radical tx

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7
Q

In what stage of breast cancer do we give neoadjuvant tx?

A

Stage III (decrease risk of dissemination)

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8
Q

Best methods of treatment in order?

A

Surgery > radiotx > systemic tx

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9
Q

WHat is RECIST?

A

Criterias for successfull tx

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10
Q

When to stop palliative tx?

A

patient does not want it
side effects > benefits
Better quality of life before
No response

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11
Q

Define predictive factor

A

condition that can be used to predict wether a person’s cancer will respond to a specific tx

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12
Q

Define Prognostic factor

A

Condition used to estimate the change of recovery from a disease or the chance of the disease recurring

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13
Q

Define Incidence

A

New cases of disease, divided by the total population

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14
Q

Define Prevalence

A

all cases of a disease in a specified period of time, scaled to the size of that population

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15
Q

Define mortality

A

Number of deaths due to a specific cause, scaled to the size of that population

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16
Q

What can tumor markers be used for?

A

Screening
prognostic factors
diagnosis
monitoring

17
Q

Which tumor markers seen in germinal tumors?

A

b hCG, AFP, LDH

18
Q

What does level of tumor markers in germinal tumors tell you?

A

Prognosis

19
Q

Which tumor marker in prostate cancer?

What value does it have?

A

PSA

Prognostic value

20
Q

Which tumor marker in medullary thyroid ca?

A

calcitonin

21
Q

Which tumor marker in ovarian cancer?

A

CA 125

22
Q

Which tumor marker in hepatocellular ca?

A

AFP

23
Q

Which tumor marker in breast cancer?

A

NO TM IN BREAST CA!!!

24
Q

Which tumor marker in pancreatic and gastric ca?

A

CA 19-9

25
Q

In which cancer MAY palliative chemotx reverse a dissemination?

A

Testicular ca

Colorectal ca

26
Q

Which other place than in cervix may HPV cause cancer?

A

Throat!!!

27
Q

Which drugs are cardiotoxic?

A

Antracyclines (Doxorubicine)

Trastuzumab

28
Q

Which drugs are nephrotoxic?

A

Cisplatin

Methotrexate

29
Q

WHich drugs are pulmotoxic?

A

Bleomycine

30
Q

Which drugs are neurotoxic?

A

Vincristine
Cisplatin
Paclitaxel

31
Q

Which drugs are bladder-toxic?

A

Cyclophosphamide

32
Q

What does Zubrod’s scale assess?

A

Performance status

33
Q

WHat is important to remember about stage 3,4,5 in Zubrow’s scale?

A

ONLY supportive care! SHould NOT be given systemic tx

Medicine, oncology (15 decks)

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