Principles of Chemotherapy Flashcards
1
Q
What is the cell cycle?
A
G0- resting G1- RNA & protein synthesis S- DNA synthesis G2- cells constructing mitotic apparatus M- cell division
2
Q
What is PMAT
A
Prophase
Metaphase
Anophase
Telophase
3
Q
What are the classes of chemo?
A
alkalating agents antitumor anibiotics antimetabolites Vinca alkoloids campthothecins misc agents
4
Q
alkalating agents
A
non specific
5
Q
antitumor antibiotics
A
cell cycle specific phase nonspecific
6
Q
antimetabolites
A
s phase
7
Q
vinca alkolides
A
m phase
8
Q
campthothecins
A
s phase
9
Q
taxanes
A
m phase
10
Q
podohyllotoxins
A
m phase
11
Q
routes for administrations
A
systemic -oral -IV -subcutaneous -intramuscular Regional -intrathecal -intraarterial -intracavitary
12
Q
Chemo side effects
A
severity of effects varies according to dosage, timing, duration, route of administration, prior chemo and radiation
13
Q
what is MDR
A
multi drug resistant gene
