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Flashcards in Prophylactic antibiotics in surgery Deck (11)
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1
Q

Why are prophylactic antibiotics used in surgery?

A
  • Reduce risk of surgical wound infection
2
Q

What measures can be taken to reduce risk of wound infection?

A
  • Time antiobiotic administration correctly
    • IV prophylaxis 30 min prior to maximize skin concentration
    • Metronidazole PR is given 2 hours before
  • Antibiotics should work against anaerobes and coliforms
  • Peri-operative supplement oxygen can reduce wound infection incidence
  • Practice strictly sterile surgical techniques
3
Q

What is the peri-operative antibiotic regimen to reduce wound infection risk in Appendicetomy, coloerctal resections and open biliary surgery?

A
  • Single dose of IV piperacillin or gentamicin
    • metronidazole or co-amoxiclav
4
Q

What is the peri-operative antibiotic regimen to reduce wound infection risk in oesophageal or gastric?

A
  • IV piperacillin or gentamicin
    • metrondazole or co-amoxiclav
5
Q

What is the peri-operative antibiotic regimen to reduce wound infection risk in vascular surgery?

A
  • IV piperacillin or flucloxacillin
    • gentamicin
  • Add metronidazole if risk of anaerobes (amputations, gangrene, diabetes)
6
Q

What antibiotics can be added if a person with MRSA is going for surgery?

A
  • Vancomycin
  • or Teicoplanin
7
Q

What is meant by a clean surgical site and what is the infection risk?

A
  • Incising uninfected skin without opening a viscus
  • <2% infection risk
8
Q

What is meant by a clean-contaminated surgical site and what is the infection risk?

A
  • Intra-operative breach of a viscus (not colon)
  • 8-10% infection risk
9
Q

What is meant by a contaminated surgical site and what is the infection risk?

A
  • Breach of a viscus + spillage or opening of colon
  • 12-20% infection risk
10
Q

What is meant by a dirty surgical site and what is the infection risk?

A
  • Site is already contamined with pus or faeces, or from exogenous contagion
  • 25% infection risk
11
Q

Teach me surgery guidelines to prophylactic antibiotic therapies for specific procedures

A