Prostate ca Flashcards

1
Q

Abiratarone

A

Peripheral androgen synthesis inhibitor
17CYP pathway
Inhibits 17α-hydroxylase (CYP17), key enzyme in steroid synthesis
Keyside effects
- Fluid retention, hypertension
- Hypokalemia
Must be used in combination with prednisolone

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2
Q

GnRH antagonist

A

Degarelix

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3
Q

GnRH agonist

A

goserelin, leuprolide

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