Protein Processing and Targeting Flashcards Preview

Semester 1- MGD > Protein Processing and Targeting > Flashcards

Flashcards in Protein Processing and Targeting Deck (4)
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1
Q

Describe regulated secretion of proteins

A

Proteins are packaged into vesicles and only released when they are required

2
Q

When a protein is targeted to the Golgi, what occurs first?

A

O-linked glycosylation using glycosyl transferase

3
Q

Describe the stages of making insulin in the body

A

Preproinsulin is secreted- 3 peptide and a signal sequence
Signal removed to become Proinsulin
C peptide removed to leave A and B peptides attached by disulphide bonds. This is mature insulin.

4
Q

Describe constitutive secretion of proteins

A

Continuous process where proteins are packaged and released constantly via exocytosis