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Flashcards in Receptor Functions Deck (10)
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1
Q

What are the α1 receptor functions?

A

Constriction!

  1. Constrict Blood Vessels
  2. Constrict Intestines and Bladder sphinctors
  3. Constrict pupilary dialators
2
Q

What are the α2 receptor functions?

A
  1. Decrease Sympathetic Nervous System outflow (“i” type G-protein.)
  2. Dec Insulin release
  3. Smooth muscle RELAXATION in GI
3
Q

What are the β1 receptor functions?

A
  1. Increase Heart Rate and Contractility
  2. Inc Renin (Beta boosts, 1 in in renin=B1)
  3. Inc lipolysis
4
Q

What are the β2 receptor functions?

A

DILATE AND RELAX BOY

  1. Vasodilation (A1B2CD)
  2. Bronchodilation
  3. “Dilation in intraoptic canals” leading to INC Intraocular Presure and inc aqueous humor production
  4. Dilate the GI Smooth muscle (aka relax it)
  5. Dilate uterine smooth muscle (aka relax)
5
Q

What are the β3 receptor functions?

A
  1. Relaxes Bladder Wall Muscles
  2. Inc lipolysis
6
Q

True or false: Muscarinic receptor activation causes bronchial muscle contraction.

A

True

Bronchodilation is B2

7
Q

What are the NN receptor functions?

A
  1. Sympathetic CV effect (at autonoic ganglia)
  2. Parasympathetic GI/GU effects (at autonoic ganglia)
  3. Mild alerting effect (CNS, may lead to convulsions if OD)
  4. Reward pathway (CNS)
8
Q

Which type of Nicotinic receptor can lead to depolarization blockage?

A

Nm=muscle paralysis

9
Q

What are the side effects of muscarinic cholenergic agonists?

A

SLUDGE BB

Saliva

Lacrimation

Urination

Diarrhea

GI

Eyes –>constriction

Bradycardia and Bronchospasms

10
Q

Which receptor relaxes RENAL vascular smooth muscle?

A

D1 (dopamine)