Resting potential Flashcards Preview

Y1 Neuroscience and Mental Health > Resting potential > Flashcards

Flashcards in Resting potential Deck (13)
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1
Q

What is flux?

A

Number of molecules that cross a unit area per unit time

In dynamic equilibrium there is no net flux

2
Q

What is voltage?

A

Generated by ions to produce a charge gradient - potential difference

3
Q

What is current

A

Movement of ions due to a potential difference

4
Q

What is resistance?

A

Barrier that prevents movement of ions

5
Q

What is the resting membrane potential

A

Found in all cells ~70mV in nerve cells

6
Q

What is an ion channel?

A

A pore that allows for gating (can open or close in response to ligands, mechanical or for trans membrane voltage

7
Q

What is the electrochemical equilibrium

A

Movement of ions balance between concentration gradient and electrical gradient, where flow down c-gradient offset by opposite movement caused by ion like repulsion

8
Q

What is the equilibrium potential?

A

Potential where the electrochemical equilibrium has been released, it is the potential that prevents diffusion of the ion down it’s concentration gradient

9
Q

What is the neurone membrane permeable to even at rest?

A

Slightly to Cl- and Na+

so membrane affected by conc gradients and permeability

10
Q

What is the goldman hodgkins katz equation used for?

A

Estimating the membrane potential considering the permeability and concentration gradients of K+/Na+/Cl-

11
Q

What happens to membrane potential in depolarising,
hyperpolarising,
overshoot,
repolarising

A

Depolarising: potential more positive

hyperpolarising: potential more negative
overshoot: potential more positive
repolarising: return to resting membrane potential

12
Q

What is a graded potential?

A

Change to membrane potential in response to stimulation, often occurring at synapses to integrate a number of signals and produce a response proportional to stimuli - can initiate or prevent action potentials

13
Q

What is graded decay?

A

Strength of impulse decreases as travel along axon