Reversals/anticholinergic agents Flashcards

1
Q

Atropine bolus dose

A
  1. 4 mg

0. 01 mg/kg

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2
Q

Atropine concentration

A

0.4 mg/ml

1 mg/ml

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3
Q

Atropine onset

A

60-90 seconds

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4
Q

Atropine considerations

A

+++ HR
+ CNS
- secretions

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5
Q

Glycopyrrolate bolus dose

A
  1. 2-0.4 mg

0. 01 mg/kg

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6
Q

Glycopyrrolate concentration

A

0.1 mg/ml

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7
Q

Glycopyrrolate onset

A

2-3 min

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8
Q

Glycopyrrolate duration

A

120-240 minutes

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9
Q

Glycopyrrolate considerations

A

++ HR
No CNS
– Secretions
Watch for anticholinergic side effects

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10
Q

Glycopyrrolate class

A

Anticholinergic

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11
Q

Atropine class

A

Anticholinergic

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12
Q

Nestigmine class

A

Anticholinesterases

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13
Q

Neostigmine dose

A

0.02-0.08 mg/kg

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14
Q

Neostigmine max dose

A

5 mg

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15
Q

Nestigmine concentration

A

1 mg/ml

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16
Q

Neostigmine onset

A

7 min

17
Q

Neostigmine duration

A

55-75 min

18
Q

Neostigmine metabolism

A

50/50 liver/renal

19
Q

Usual neostigmine/glycopyrrolate dose

A

1 mg neostigmine/0.2 mg glycopyrrolate

20
Q

Edrophonium dose

A

0.5-1 mg/kg

21
Q

Edrophonium concentration

A

10 mg/ml

22
Q

Edrophonium onset

A

1-2 min

23
Q

Edrophonium duration

A

15-60 min

24
Q

Edrophonium metabolism

A

70 renal/ 30 hepatic

25
Q

Usual edrophonium/atropine ratio

A

1 mg edrophonium/0.4 mg atropine