ROS and Antioxidants Test Q's Flashcards Preview

IHO week 5 > ROS and Antioxidants Test Q's > Flashcards

Flashcards in ROS and Antioxidants Test Q's Deck (5)
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1
Q

Impaired wound healing

Bleeding ecchymosis

swollen gums

anemia

enlargement and keratosis of hair follicles

lethargy

depression

A

Vitamin C deficiency

aka

Scurvy

2
Q

Found primarily in peroxisomes

highest in kidney and liver

reduces H2O2 to water to prevent it from forming hydroxyl radical via Fenton or Haber-Weiss rxns

A

Catalase

3
Q

Converts superoxide into hydrogen peroxide and O2

primary defense against oxidative stress

implicated in ALS !!!!

A

superoxide dismutase

4
Q

Caused by ROS derived from O2 in the blood that reenters previously hypoxic cells

Insufficiebt O2 = decreased ATP

Decreased ATP = increased Na+ and Ca2+

A

Ischemia-reperfusion injury

5
Q

life threatening recurrent infx from catalase POSITIVE organisms

genetic defect in NADPH oxidase

caseous necrosis

A

Chronic Granulomatous disease