RPGN Flashcards Preview

Nelson - Nephrology > RPGN > Flashcards

Flashcards in RPGN Deck (7):
1

RPGN is AKA

Crescentic GN

2

Population of patients that appear to be particularly prone to CGN

Patients with systemic vasculitis

3

Hallmark of CGN

Glomerular crescents

4

Crescents in CGN consists of

Proliferation of parietal epithelial cells in the Bowman's space

5

CGN with rare or absent findings on EM and IF

1) Pauciimune GN (Wegener disease and microscopic polyangiitis 2) Idiopathic crescentic GN

6

T/F Children with crescentic post-infectious GN can spontaneously recover

T

7

May be effective in preventing progressive renal failure in patients with SLE, HSP nephritis, Wegener granulomatosis, and IgA nephropathy if given early in the course when acute cellular crescents predominate

High-dose corticosteroids and cyclophosphamide