Flashcards in Rubella Deck (22)
genus of Rubella
false about Rubella
A.one antigenic type
C.single strand positive sense RNA
Rubella glycoprotein components: enumerate
host cell derived lipid
icosahedral nucleocapsid components:enumerate
enumerate 3 major virion polypeptides of rubella virus
antigen in rubella that agglutinates chick, pigeon, goose and type O human RBC
Where does rubella virus replicate?
Which is false?
A. Rubella is zoonotic.
B. Rubella may be transmitted via inhalational or transplacental.
C. Peak of rubella infection is during late winter and spring.
D. Rubella is communicable 7 days before and after the onset.
humans: only host
In postnatal rubella, in what organ does the virus replicate?
T or F: Placenta and fetus may be infected in viremia of postnatal rubella.
Sequence the clinical features of rubella
A. Maculopapular rash
B C A
Identify enanthem of rubella + locatiion
Forschheimer spots @ soft palate
most common complication of postnatal rubella
False about Rubella reinfection
A. occurs in a person with natural rubella or vaccine
B. IgG antibody response is higher with equiocal IgM titer
C. uncommon to cause unequivocal fetal damage
D. with visible symptoms
most common manif of Congenital Rubella Syndrome
intrauterine growth retardation
most common clinical feature of Congenital Rubella Syndrome
slow cell div, disoriented cell diff, small BV damages: in what trim does this occur?
Specific Ig @ less than __ months indicates (+) Congenital Rubella
if 9-12 months, check if there's maternal Ab inteference
method of choice for Congenital Rubella diagnosis indluse all except:
C.immunofluorescent absorbent assay
passive prophylaxis of rubella
live virus for rubella artificial active immunity -- what is the composition?
RA 27/3 Strain