Samplex 1st LE Flashcards Preview

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Flashcards in Samplex 1st LE Deck (34)
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1
Q

This protein attaches to membrane proteins destined for endocytosis and eventual degradation in the lysosomes

A

Ubiquitin

2
Q

Proteins destined to be secreted or targeted out of the plasma membrane are processed in the…

A

Rough ER

3
Q

Type of diffusion where carrier undergoes conformational change:

A

Facilitated diffusion

4
Q

Co transport molecule of glucose

A

Sodium

5
Q

Used for cholesterol uptake

A

Receptor- mediated endocytosis

6
Q

A form of bull transport by which a hormone is secreted when the appropriate signal is received by the cell is:

A

Regulated exocytosis

7
Q

Phosphorylation of g protein coupled receptor results in

A

Inactivation of receptor

8
Q

Activation of this effector g protein results in the activation of creb protein

A

Adenylyl cyclase

9
Q

Activation of plc results in an increase of cytosolic calcium because of the opening of

A

Ip3 gated calcium channels in the erStore operated calcium channels

10
Q

Binding of a ligand to a tyrosine kinase receptor causes

A

Autophosphorylation of the receptor

11
Q

Cytokine receptors acitvate loosely associated tyrosine kinases known as

A

JAK

12
Q

Transcription factor activated by receptor serine-threonjbe kinase

A

SMAD

13
Q

Phosphorylated insulin receptor can activate this

A

MAPK

14
Q

Receptor for ligand epinephrine

A

G protein coupled receptor

15
Q

Receptor for estrogen

A

Intracellular

16
Q

Receptor for TGF-B

A

Serine threonine kinase receptor

17
Q

Neuron that sends impukses towards the cns

A

Afferent unipolar

18
Q

In rmp, ions move through which channel

A

Leak channels

19
Q

Local potential exhibited by a sensory neuron

A

Generator potential

20
Q

Equation on concentration of ions in rmp

A

GoldmanHodgkinKatz

21
Q

The spike potential determines this neuron property

A

Excitability

22
Q

The duration of action potential is the

A

Spike potential

23
Q

The critical firing level

A

Threshold potential

24
Q

Hyperpolarization occurs during what period

A

Relative refractory period

25
Q

Toxin that blocks voltage gated sodium channels; from puffer fish

A

Tetrodotoxin

26
Q

Toxin blocks nmj ach receptor; from snake venom

A

Bungarotoxin

27
Q

Blocks voltage gated potassium channels

A

Apamin from honeybee

28
Q

Viltage gated sodium channel is most dense at the

A

Nodes of ranvier

29
Q

Susceptibility trend to hypoxia

A

B>A>C

30
Q

Neuron fiber susceptibility to pressure

A

ABC

31
Q

Neuron fiber susceptibility to local anesthetics

A

CBA

32
Q

Increases the likelihood of an action potential on the PSN

A

Temporal and spatial summation

33
Q

Is the simultaneous firing of neurons

A

Spatial summation

34
Q

Increasing the frequency if stimulation of the neurons

A

Temporal summation