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Flashcards in Sarcoidosis Deck (7)
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1

What is sarcoidosis

a multisystem disorder of unknown cause characterised by non-caseating granulomas. It is more common in young adults and african people

2

Features of Sarcoidosis

Acutely -- erythema nodosum, bilateral hilar lymphadenopathy, a 'swinging' fever and polyarthralgia.
Insidious -- dyspnoea, non-productive cough, malaise & weight loss
Can have lupus pernio and hypercalcaemia

3

Lofgren's Syndromes

an acute form with bilateral hilar lymphadenopathy (BHL), erythema nodosum, fever and polyarthralgia. it usually has an excellent prognosis

4

Heerfordt's syndrome

Uveoparotid fever - parotid enlargement with fever and uveitis secondary to sarcoidosis

5

Why does sarcoidosis give you hypercalcaemia?

Macrophages in the granulomas cause increased conversion of Vit D to its active form

6

Lupus pernio

Chronic, raised and hardened purplish lesion of the skin on face, hands or fingers. resembles frost bite.

7

Treat with steroids if

Hypercalcaemia, worsening lung function or heart, eye or neurological involvement.