Flashcards in Sarcoidosis Deck (7)
What is sarcoidosis
a multisystem disorder of unknown cause characterised by non-caseating granulomas. It is more common in young adults and african people
Features of Sarcoidosis
Acutely -- erythema nodosum, bilateral hilar lymphadenopathy, a 'swinging' fever and polyarthralgia.
Insidious -- dyspnoea, non-productive cough, malaise & weight loss
Can have lupus pernio and hypercalcaemia
an acute form with bilateral hilar lymphadenopathy (BHL), erythema nodosum, fever and polyarthralgia. it usually has an excellent prognosis
Uveoparotid fever - parotid enlargement with fever and uveitis secondary to sarcoidosis
Why does sarcoidosis give you hypercalcaemia?
Macrophages in the granulomas cause increased conversion of Vit D to its active form
Chronic, raised and hardened purplish lesion of the skin on face, hands or fingers. resembles frost bite.