Skin Cancer Flashcards

1
Q

What are the 2 main types of skin cancer

A

Non-melanoma skin cancer

Melanoma

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2
Q

Where do the majority of non-melanoma skin cancers arise from

A

Keratinocytes within the dermis

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3
Q

Where do BCC arise from

A

Keratinocytes within the basal layer of the epidermis

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4
Q

Where do SCC arise from

A

Suprabasal layers

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5
Q

Where does melanoma arise from

A

pigment-forming cells (melanocytes) which are scattered along the basal layer of the epidermis

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6
Q

What is causing an increase in incidence of skin cancer in scotland

A

More sun exposure due to more holidays
More sunbed use
More diagnostic opportunity

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7
Q

What type of skin cancer is the fastest increasing cancer in scotland

A

Melanoma

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8
Q

How do BCCs usually present

A

As a translucent, slow growing lump or a non-healing ulcer

Painless

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9
Q

How do SCCs present

A

Warty or crusted growth or a non-healing ulcer
usually in sun exposed areas and they grow faster.
Pain and have the ability to spread

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10
Q

Twice as many young women get melanoma but more men die. True or false

A

true

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11
Q

The survival of melanoma depends on what

A

Tumour depth

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12
Q

The 5 year survival rate for melanoma is great if the depth of the tumour is less than what?

A

1mm

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13
Q

In terms of dermatology and melanoma, what does ABCDE stand for

A
Asymmetry
Border
Colour
Diameter
Evolution
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14
Q

Odd looking moles are often termed as what

A

Ugly duckling sign

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15
Q

Why do some sites become ulcerated

A

Due to the poor blood supply

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16
Q

Melanomas are sometimes confused with what

A

Pigmented BCC

17
Q

Are squamous cell carcinomas usually well differentiated or poorly differentiated

A

Well differentiated

18
Q

What are Actinic Keratoses

A

Precancerous skin lesions

19
Q

Describe the appearance of Bowen’s disease

A

erythematous plaque commonly found on the legs of older women

20
Q

What is common in a keratoacanthoma

A

Central crater

21
Q

What areas of the body are high risk for SCCs

A

Ear, scalp and lip

22
Q

Where are common metastatic areas of SCCs

A

Lymph nodes and bones

23
Q

What are some risk factors for skin cancer

A
Sun exposure
Genetic predisposition
Immunosuppression
HPV infection 
Smoking, ionising radiation
24
Q

How many skin types are there?

A

6

25
Q

What does skin colour dictate

A

How sensitive you are to sun and your risk for getting skin cancer

26
Q

Childhood sunburn increases the melanoma risk by what

A

4-fold

27
Q

What type of genetic conditions increase your risk for developing skin cancer

A

Hereditary Type VII collagen deficiency
Recessive dystrophic epidermolysis bullosa
Naevoid basal cell carcinoma (Gorlin’s syndrome)
Oculocutaneous albinism
Xeroderma Pigmentosum