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Flashcards in Sympathometics Deck (22)
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1
Q

Which groups can we split sympathomimetics in?

A

Non-specific and specific.

2
Q

Which groups do we split the specific sympathomimetics in?

A

Beta-adrenoreceptor agonist, alpha-adrenoreceptor agonists

3
Q

what are the non-specific sympathomimetic drugs?

A

Adrenaline, Noradrenaline and dopamine

4
Q

Which drugs are Beta-adrenoreceptor agonists?

A

Dobutamine, clenbuterol,solbutamole, terbutaline, salmeterole, isoxsuprine

5
Q

Which drugs are Alpha-adrenoreceptor agonists?

A

Phenylephrine, Xylometazoline, oxymetazoline, naphazoline, tetryzoline, Phenylproponolamine, ephrine, Amphetamine, Xylazine, detomidone, medetomidine, romifidine

6
Q

Receptors of Adrenaline :

A

Mainly B1 and B2 receptors, but increased dose affects alpha1 receptors too.

7
Q

Receptors of Noradrenaline

A

mainly B1 and A1 receptors;

  • Cardiac effect
  • Blood pressure is significantly increased; -Cardiac effect – arrhythmia can be caused
  • Arrhythmogenic
8
Q

Receptors of dopamine:

A

Low dose D1 receptors (kidney, increased glomerular filtration rate, renal failure, increased blood circulation)

  • Medium dose B1-receptors (heart)
  • High dose A1-receptors (pressor)
9
Q

Indications of Adrenaline

A
  • cardiac stop
  • severe bronchoconstriction
  • anaphylaxia(3 agents: Adrenaline, glucocorticoids, antihistamine)
  • local vasoconstriction (stops haemorrhages)
  • increase in duration of local anaesthetics
  • Lidocain + adrenaline combo
10
Q

Indications of Noradrenaline

A

(rare)

-Hypotensin (low blood pressure)

11
Q

Indications of Dopamine

A
  • Constrict blood supply

- shock

12
Q

Receptors of: Dobutamine:

A

Mainly alpha1, vasoconstriction

13
Q

Receptors of: Beta2-agonists:

  • Clenbuterole
  • Salbutamole
  • Terbutaline
  • Isoxsuprine
A
  • Mainly beta 2 receptors
  • Bronchodilatation
  • Uterus relaxation

Higher dosage beta1-receptors cardiac effect

14
Q

Receptors of: Phenylephrine:

A

Mainly alpha1-receptors vasoconstriction

15
Q

Receptors of Xylometazoline, Oxymetazoline, naphazoline, tetryzoline:

A

-Mainly alpha 1 receptors vasoconstriction

16
Q

Receptors of: Phenylpropanolamine

A

Mainly alpha1 receptors urinary bladder sphincter constriction!

17
Q

effects and indications of: Ephedrine

A

Effects: Nonspecific, direct and indirect effects.
Tachyphylaxis
CNS.
Indication: -Allergy,incontinence

18
Q

Indications of :Dobutamine:

A

-cardiogenic shock (IV infusion)

19
Q

Indications of : Clenbuterole

  • Salbutamole
  • Terbutaline
  • Isoxsuprine
A
  • Horse RAO
  • Feline asthma
  • Bronchitis,bronchopneumonia
  • Tracheal hypoplasia
  • Tracheal collapse
20
Q

Indications of :Phenylephrine:

A

-Used rarly, but local (allergy,cold) or systemic usage (hypotension,shock)

21
Q

Indications of : Xylometazoline, Oxymetazoline, naphazoline, tetryzoline:

A

-Local usage, rebound syndrome

22
Q
What are -Xylazine
-Detomidine
-Medetomidine
-Romifidine 
used for?
A

Sedato hypnotics